BRD-A22032524_AMLODIPINE BESYLATE_HA1E_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

80 genes differentially expressed following the BRD-A22032524_AMLODIPINE BESYLATE_HA1E_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ALDOC aldolase C, fructose-bisphosphate
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
BST2 bone marrow stromal cell antigen 2
C14ORF132 chromosome 14 open reading frame 132
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CD300A CD300a molecule
CLGN calmegin
CTSK cathepsin K
DPYSL2 dihydropyrimidinase-like 2
DUSP4 dual specificity phosphatase 4
EBP emopamil binding protein (sterol isomerase)
ENO2 enolase 2 (gamma, neuronal)
FADS1 fatty acid desaturase 1
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FTH1 ferritin, heavy polypeptide 1
FYB FYN binding protein
G0S2 G0/G1 switch 2
GCH1 GTP cyclohydrolase 1
GDF15 growth differentiation factor 15
GNPDA1 glucosamine-6-phosphate deaminase 1
GNS glucosamine (N-acetyl)-6-sulfatase
GPNMB glycoprotein (transmembrane) nmb
GRN granulin
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HMOX1 heme oxygenase 1
HOXB6 homeobox B6
HOXC6 homeobox C6
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IRS2 insulin receptor substrate 2
ISG15 ISG15 ubiquitin-like modifier
ITGB5 integrin, beta 5
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MMP12 matrix metallopeptidase 12
MMP9 matrix metallopeptidase 9
PRKCA protein kinase C, alpha
PTPRK protein tyrosine phosphatase, receptor type, K
RAB29 RAB29, member RAS oncogene family
RRAGD Ras-related GTP binding D
SPON2 spondin 2, extracellular matrix protein
SPP1 secreted phosphoprotein 1
SPRY2 sprouty homolog 2 (Drosophila)
SQSTM1 sequestosome 1
TMBIM6 transmembrane BAX inhibitor motif containing 6
TRAPPC6A trafficking protein particle complex 6A
VAT1 vesicle amine transport 1
VEGFA vascular endothelial growth factor A
VGLL4 vestigial-like family member 4
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae)

decreased expression

Symbol Name
BZW2 basic leucine zipper and W2 domains 2
CA1 carbonic anhydrase I
CAV1 caveolin 1, caveolae protein, 22kDa
CCL2 chemokine (C-C motif) ligand 2
CFLAR CASP8 and FADD-like apoptosis regulator
CLIC3 chloride intracellular channel 3
EMP1 epithelial membrane protein 1
GPRC5A G protein-coupled receptor, class C, group 5, member A
H2BFS H2B histone family, member S (pseudogene)
HBD hemoglobin, delta
HIST1H2AC histone cluster 1, H2ac
IGKC immunoglobulin kappa constant
IGL immunoglobulin lambda locus
IL1R1 interleukin 1 receptor, type I
LRRC17 leucine rich repeat containing 17
MAOA monoamine oxidase A
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
P3H2 prolyl 3-hydroxylase 2
PON2 paraoxonase 2
RGCC regulator of cell cycle
S100A8 S100 calcium binding protein A8
TGFBI transforming growth factor, beta-induced, 68kDa
THBS1 thrombospondin 1
TPM2 tropomyosin 2 (beta)
TSPAN13 tetraspanin 13
TTN titin
TXNDC9 thioredoxin domain containing 9