BRD-A21584801_brivanib_BT20_3_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

34 genes differentially expressed following the BRD-A21584801_brivanib_BT20_3_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AZU1 azurocidin 1
BEX1 brain expressed, X-linked 1
CTSG cathepsin G
ELANE elastase, neutrophil expressed
ENAH enabled homolog (Drosophila)
GATA3 GATA binding protein 3
JUN jun proto-oncogene
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
NGRN neugrin, neurite outgrowth associated
NPDC1 neural proliferation, differentiation and control, 1
SFRP1 secreted frizzled-related protein 1
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)

decreased expression

Symbol Name
ADA adenosine deaminase
AEBP1 AE binding protein 1
AQP3 aquaporin 3 (Gill blood group)
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
CLIC3 chloride intracellular channel 3
CLTB clathrin, light chain B
COL11A1 collagen, type XI, alpha 1
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15
H2BFS H2B histone family, member S (pseudogene)
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
KLK10 kallikrein-related peptidase 10
KLK11 kallikrein-related peptidase 11
LEF1 lymphoid enhancer-binding factor 1
MAL mal, T-cell differentiation protein
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
NMU neuromedin U
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
TGFBI transforming growth factor, beta-induced, 68kDa