BRD-A21584801_brivanib_BT20_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

32 genes differentially expressed following the BRD-A21584801_brivanib_BT20_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
CPE carboxypeptidase E
DAPK1 death-associated protein kinase 1
EFNB2 ephrin-B2
FOLR1 folate receptor 1 (adult)
GLG1 golgi glycoprotein 1
KCTD12 potassium channel tetramerization domain containing 12
MYO6 myosin VI
PDLIM5 PDZ and LIM domain 5
SCG2 secretogranin II
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SOX9 SRY (sex determining region Y)-box 9
STC2 stanniocalcin 2
VCAN versican

decreased expression

Symbol Name
CD44 CD44 molecule (Indian blood group)
CXCL8 chemokine (C-X-C motif) ligand 8
FGFR3 fibroblast growth factor receptor 3
G0S2 G0/G1 switch 2
GDF15 growth differentiation factor 15
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
LEF1 lymphoid enhancer-binding factor 1
NPEPL1 aminopeptidase-like 1
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
RHOBTB3 Rho-related BTB domain containing 3
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
S100A8 S100 calcium binding protein A8
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SORD sorbitol dehydrogenase
SPON2 spondin 2, extracellular matrix protein
TRIB2 tribbles pseudokinase 2
ZBTB20 zinc finger and BTB domain containing 20