BRD-A21406558_NCGC00229595-01_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

42 genes differentially expressed following the BRD-A21406558_NCGC00229595-01_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
BAG3 BCL2-associated athanogene 3
BASP1 brain abundant, membrane attached signal protein 1
CFD complement factor D (adipsin)
CHI3L2 chitinase 3-like 2
DDIT4 DNA-damage-inducible transcript 4
DLD dihydrolipoamide dehydrogenase
FOXO4 forkhead box O4
HOXC6 homeobox C6
KRT14 keratin 14, type I
LEF1 lymphoid enhancer-binding factor 1
LEPR leptin receptor
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MARCKS myristoylated alanine-rich protein kinase C substrate
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
NR2F2 nuclear receptor subfamily 2, group F, member 2
PRAME preferentially expressed antigen in melanoma
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFRP1 secreted frizzled-related protein 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SORBS3 sorbin and SH3 domain containing 3
SSFA2 sperm specific antigen 2
SVIL supervillin
TBC1D4 TBC1 domain family, member 4
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TGFBI transforming growth factor, beta-induced, 68kDa
XBP1 X-box binding protein 1

decreased expression

Symbol Name
C3ORF14 chromosome 3 open reading frame 14
CCND2 cyclin D2
CD9 CD9 molecule
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CPE carboxypeptidase E
GPX2 glutathione peroxidase 2
HIST1H4C histone cluster 1, H4c
KLK5 kallikrein-related peptidase 5
MCL1 myeloid cell leukemia 1
RGS2 regulator of G-protein signaling 2
SPINK1 serine peptidase inhibitor, Kazal type 1
THBS2 thrombospondin 2
WT1 Wilms tumor 1