BRD-A20968261_-666_SKB_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

161 genes differentially expressed following the BRD-A20968261_-666_SKB_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AEBP1 AE binding protein 1
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
ARG1 arginase 1
AUTS2 autism susceptibility candidate 2
BCL2 B-cell CLL/lymphoma 2
BDH1 3-hydroxybutyrate dehydrogenase, type 1
BHMT2 betaine--homocysteine S-methyltransferase 2
CADM1 cell adhesion molecule 1
CCL4 chemokine (C-C motif) ligand 4
CCR7 chemokine (C-C motif) receptor 7
CD83 CD83 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CLU clusterin
COL11A1 collagen, type XI, alpha 1
COLEC11 collectin sub-family member 11
CP ceruloplasmin (ferroxidase)
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYTH1 cytohesin 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DLK1 delta-like 1 homolog (Drosophila)
EGR3 early growth response 3
EREG epiregulin
ETV1 ets variant 1
FAM117A family with sequence similarity 117, member A
FOLR1 folate receptor 1 (adult)
FRS2 fibroblast growth factor receptor substrate 2
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GPR183 G protein-coupled receptor 183
GPX3 glutathione peroxidase 3
HAL histidine ammonia-lyase
HBB hemoglobin, beta
HP haptoglobin
IL1B interleukin 1, beta
IL7R interleukin 7 receptor
INHBA inhibin, beta A
ITK IL2-inducible T-cell kinase
JARID2 jumonji, AT rich interactive domain 2
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KDM5D lysine (K)-specific demethylase 5D
KLK8 kallikrein-related peptidase 8
LAMP3 lysosomal-associated membrane protein 3
LAPTM4B lysosomal protein transmembrane 4 beta
LIG1 ligase I, DNA, ATP-dependent
LTF lactotransferrin
MYB v-myb avian myeloblastosis viral oncogene homolog
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PDZK1 PDZ domain containing 1
PLAC8 placenta-specific 8
PRSS21 protease, serine, 21 (testisin)
PRUNE prune exopolyphosphatase
PTPN6 protein tyrosine phosphatase, non-receptor type 6
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBP4 retinol binding protein 4, plasma
RHOBTB3 Rho-related BTB domain containing 3
RUNX3 runt-related transcription factor 3
SELL selectin L
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SH2D1A SH2 domain containing 1A
SPON1 spondin 1, extracellular matrix protein
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
STAR steroidogenic acute regulatory protein
SYNE1 spectrin repeat containing, nuclear envelope 1
TCF4 transcription factor 4
TNC tenascin C
TREM1 triggering receptor expressed on myeloid cells 1
WFDC2 WAP four-disulfide core domain 2

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ACAT2 acetyl-CoA acetyltransferase 2
ACSL3 acyl-CoA synthetase long-chain family member 3
ADI1 acireductone dioxygenase 1
AHNAK2 AHNAK nucleoprotein 2
AKR1C3 aldo-keto reductase family 1, member C3
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
BSG basigin (Ok blood group)
C3ORF14 chromosome 3 open reading frame 14
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
CAPN2 calpain 2, (m/II) large subunit
CAST calpastatin
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CD44 CD44 molecule (Indian blood group)
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLIC5 chloride intracellular channel 5
COTL1 coactosin-like F-actin binding protein 1
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CSRP1 cysteine and glycine-rich protein 1
CTNND1 catenin (cadherin-associated protein), delta 1
DEGS1 delta(4)-desaturase, sphingolipid 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLD dihydrolipoamide dehydrogenase
DUSP3 dual specificity phosphatase 3
EPAS1 endothelial PAS domain protein 1
ERBB2 erb-b2 receptor tyrosine kinase 2
FABP4 fatty acid binding protein 4, adipocyte
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FADS2 fatty acid desaturase 2
FLRT2 fibronectin leucine rich transmembrane protein 2
FN1 fibronectin 1
FSTL1 follistatin-like 1
GOLT1B golgi transport 1B
GSN gelsolin
H2AFX H2A histone family, member X
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HLA-B major histocompatibility complex, class I, B
HMG20B high mobility group 20B
HSPA13 heat shock protein 70kDa family, member 13
IDI1 isopentenyl-diphosphate delta isomerase 1
IGFBP7 insulin-like growth factor binding protein 7
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KIF5B kinesin family member 5B
LAMP2 lysosomal-associated membrane protein 2
LGALS3 lectin, galactoside-binding, soluble, 3
MDFIC MyoD family inhibitor domain containing
MKNK2 MAP kinase interacting serine/threonine kinase 2
MME membrane metallo-endopeptidase
NUP85 nucleoporin 85kDa
NVL nuclear VCP-like
OLFM4 olfactomedin 4
PAWR PRKC, apoptosis, WT1, regulator
PCNA proliferating cell nuclear antigen
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
PON2 paraoxonase 2
PPIC peptidylprolyl isomerase C (cyclophilin C)
PTEN phosphatase and tensin homolog
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTRF polymerase I and transcript release factor
PYCARD PYD and CARD domain containing
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RFTN1 raftlin, lipid raft linker 1
S100A10 S100 calcium binding protein A10
S100A8 S100 calcium binding protein A8
SAT1 spermidine/spermine N1-acetyltransferase 1
SCAND1 SCAN domain containing 1
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SEPT9 septin 9
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC38A1 solute carrier family 38, member 1
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SPAG16 sperm associated antigen 16
SPINK1 serine peptidase inhibitor, Kazal type 1
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STS steroid sulfatase (microsomal), isozyme S
SYNM synemin, intermediate filament protein
TACC2 transforming, acidic coiled-coil containing protein 2
TES testin LIM domain protein
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast)
TM4SF1 transmembrane 4 L six family member 1
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TRAPPC3 trafficking protein particle complex 3
TSPAN4 tetraspanin 4
TYROBP TYRO protein tyrosine kinase binding protein
XIST X inactive specific transcript (non-protein coding)
YBX3 Y box binding protein 3