BRD-A20968261_-666_PHH_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

143 genes differentially expressed following the BRD-A20968261_-666_PHH_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ALCAM activated leukocyte cell adhesion molecule
BST2 bone marrow stromal cell antigen 2
C4BPA complement component 4 binding protein, alpha
C4BPB complement component 4 binding protein, beta
C6ORF48 chromosome 6 open reading frame 48
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2A cyclin-dependent kinase inhibitor 2A
CLU clusterin
CPVL carboxypeptidase, vitellogenic-like
CX3CR1 chemokine (C-X3-C motif) receptor 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DEFB1 defensin, beta 1
DKFZP586I1420 uncharacterized protein DKFZp586I1420
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DUSP2 dual specificity phosphatase 2
EGR3 early growth response 3
ENDOD1 endonuclease domain containing 1
FAM46A family with sequence similarity 46, member A
FOLR1 folate receptor 1 (adult)
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10
GATA3 GATA binding protein 3
HBD hemoglobin, delta
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
JADE2 jade family PHD finger 2
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KRT7 keratin 7, type II
LAPTM4B lysosomal protein transmembrane 4 beta
LEPR leptin receptor
LIF leukemia inhibitory factor
LIMCH1 LIM and calponin homology domains 1
MET MET proto-oncogene, receptor tyrosine kinase
NAV3 neuron navigator 3
NOTCH2 notch 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PGC progastricsin (pepsinogen C)
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PYCR1 pyrroline-5-carboxylate reductase 1
RPL39L ribosomal protein L39-like
RPS4Y1 ribosomal protein S4, Y-linked 1
RUNX3 runt-related transcription factor 3
SFRP1 secreted frizzled-related protein 1
SOX4 SRY (sex determining region Y)-box 4
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
STC2 stanniocalcin 2
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TFF2 trefoil factor 2
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TIAM1 T-cell lymphoma invasion and metastasis 1
TMEM243 transmembrane protein 243, mitochondrial
TMPRSS3 transmembrane protease, serine 3
TNC tenascin C
TSPAN13 tetraspanin 13
TXNIP thioredoxin interacting protein
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
USP1 ubiquitin specific peptidase 1
WFDC2 WAP four-disulfide core domain 2
WT1 Wilms tumor 1

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ACD adrenocortical dysplasia homolog (mouse)
AKAP1 A kinase (PRKA) anchor protein 1
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ANGPT2 angiopoietin 2
ASPN asporin
BEX1 brain expressed, X-linked 1
BID BH3 interacting domain death agonist
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CCND2 cyclin D2
CD44 CD44 molecule (Indian blood group)
CD52 CD52 molecule
CD99 CD99 molecule
CDK5 cyclin-dependent kinase 5
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CERS6 ceramide synthase 6
CETN2 centrin, EF-hand protein, 2
CKB creatine kinase, brain
CLEC11A C-type lectin domain family 11, member A
COL6A2 collagen, type VI, alpha 2
COQ9 coenzyme Q9
CTSK cathepsin K
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXCL13 chemokine (C-X-C motif) ligand 13
CYCS cytochrome c, somatic
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
ECM1 extracellular matrix protein 1
ENOPH1 enolase-phosphatase 1
ETHE1 ethylmalonic encephalopathy 1
FABP1 fatty acid binding protein 1, liver
FABP4 fatty acid binding protein 4, adipocyte
FAM96B family with sequence similarity 96, member B
FASN fatty acid synthase
FN1 fibronectin 1
G0S2 G0/G1 switch 2
GSPT2 G1 to S phase transition 2
HILPDA hypoxia inducible lipid droplet-associated
HIRA histone cell cycle regulator
HSPH1 heat shock 105kDa/110kDa protein 1
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGLJ3 immunoglobulin lambda joining 3
IGLV3-19 immunoglobulin lambda variable 3-19
IL13RA2 interleukin 13 receptor, alpha 2
IL17RB interleukin 17 receptor B
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
KRT13 keratin 13, type I
LRP4 low density lipoprotein receptor-related protein 4
LYZ lysozyme
MAOA monoamine oxidase A
MMP9 matrix metallopeptidase 9
MSMB microseminoprotein, beta-
MSMO1 methylsterol monooxygenase 1
MT1M metallothionein 1M
MT1X metallothionein 1X
NPEPL1 aminopeptidase-like 1
NSDHL NAD(P) dependent steroid dehydrogenase-like
OLFM4 olfactomedin 4
PCP4 Purkinje cell protein 4
PLBD1 phospholipase B domain containing 1
PLIN2 perilipin 2
PRUNE2 prune homolog 2 (Drosophila)
PTRF polymerase I and transcript release factor
REG1A regenerating islet-derived 1 alpha
RGS5 regulator of G-protein signaling 5
S100P S100 calcium binding protein P
SAT1 spermidine/spermine N1-acetyltransferase 1
SCG2 secretogranin II
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SMC1A structural maintenance of chromosomes 1A
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPON2 spondin 2, extracellular matrix protein
SPRY4 sprouty homolog 4 (Drosophila)
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae)
TUBA1A tubulin, alpha 1a
UGDH UDP-glucose 6-dehydrogenase
XIST X inactive specific transcript (non-protein coding)
ZYX zyxin