BRD-A20697603_T8902_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

116 genes differentially expressed following the BRD-A20697603_T8902_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL3 acyl-CoA synthetase long-chain family member 3
ADM adrenomedullin
AKR1C2 aldo-keto reductase family 1, member C2
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
BRD2 bromodomain containing 2
BTN3A2 butyrophilin, subfamily 3, member A2
CCND1 cyclin D1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
COL2A1 collagen, type II, alpha 1
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTH cystathionine gamma-lyase
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT4 DNA-damage-inducible transcript 4
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ERP29 endoplasmic reticulum protein 29
FAM129A family with sequence similarity 129, member A
FAM46C family with sequence similarity 46, member C
FBXO11 F-box protein 11
FCMR Fc fragment of IgM receptor
FGFR1 fibroblast growth factor receptor 1
FYB FYN binding protein
G6PD glucose-6-phosphate dehydrogenase
GADD45B growth arrest and DNA-damage-inducible, beta
HEXIM1 hexamethylene bis-acetamide inducible 1
HMOX1 heme oxygenase 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA13 heat shock protein 70kDa family, member 13
HSPA1A heat shock 70kDa protein 1A
HSPA8 heat shock 70kDa protein 8
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IDI1 isopentenyl-diphosphate delta isomerase 1
IER5 immediate early response 5
IFRD1 interferon-related developmental regulator 1
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
INSIG1 insulin induced gene 1
KDM5D lysine (K)-specific demethylase 5D
KLHL21 kelch-like family member 21
MAP2K3 mitogen-activated protein kinase kinase 3
MSX1 msh homeobox 1
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
NEU1 sialidase 1 (lysosomal sialidase)
NKX3-1 NK3 homeobox 1
NQO1 NAD(P)H dehydrogenase, quinone 1
NRN1 neuritin 1
NUPL1 nucleoporin like 1
PPAP2B phosphatidic acid phosphatase type 2B
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PSAP prosaposin
PTRF polymerase I and transcript release factor
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RND1 Rho family GTPase 1
RPL38 ribosomal protein L38
SAT1 spermidine/spermine N1-acetyltransferase 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SQSTM1 sequestosome 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STOM stomatin
TBC1D4 TBC1 domain family, member 4
TFF3 trefoil factor 3 (intestinal)
TIMP4 TIMP metallopeptidase inhibitor 4
TMEM97 transmembrane protein 97
TNPO1 transportin 1
TSC22D3 TSC22 domain family, member 3
TUBB2A tubulin, beta 2A class IIa
VAT1 vesicle amine transport 1
XBP1 X-box binding protein 1

decreased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ADAM12 ADAM metallopeptidase domain 12
ANKRD36B ankyrin repeat domain 36B
BID BH3 interacting domain death agonist
CCND2 cyclin D2
CD1E CD1e molecule
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CLC Charcot-Leyden crystal galectin
CXCL12 chemokine (C-X-C motif) ligand 12
DACH1 dachshund family transcription factor 1
DAPK1 death-associated protein kinase 1
DPYSL3 dihydropyrimidinase-like 3
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGFL6 EGF-like-domain, multiple 6
F13A1 coagulation factor XIII, A1 polypeptide
FBN1 fibrillin 1
FHL1 four and a half LIM domains 1
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
INHBA inhibin, beta A
KCTD12 potassium channel tetramerization domain containing 12
LAMP3 lysosomal-associated membrane protein 3
LGALS1 lectin, galactoside-binding, soluble, 1
MTA1 metastasis associated 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NR2F2 nuclear receptor subfamily 2, group F, member 2
NREP neuronal regeneration related protein
PAX6 paired box 6
PBX3 pre-B-cell leukemia homeobox 3
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PDLIM3 PDZ and LIM domain 3
PXDN peroxidasin
SFRP4 secreted frizzled-related protein 4
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SOX11 SRY (sex determining region Y)-box 11
SOX9 SRY (sex determining region Y)-box 9
SPON1 spondin 1, extracellular matrix protein
TDO2 tryptophan 2,3-dioxygenase
TMEM176A transmembrane protein 176A
TMEM176B transmembrane protein 176B
TSPAN8 tetraspanin 8
XIST X inactive specific transcript (non-protein coding)
ZEB1 zinc finger E-box binding homeobox 1
ZNF22 zinc finger protein 22