BRD-A20697603_T8902_PHH_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

79 genes differentially expressed following the BRD-A20697603_T8902_PHH_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BAG3 BCL2-associated athanogene 3
CBR3 carbonyl reductase 3
DEGS1 delta(4)-desaturase, sphingolipid 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EGR1 early growth response 1
EMP1 epithelial membrane protein 1
ENC1 ectodermal-neural cortex 1 (with BTB domain)
FAM46A family with sequence similarity 46, member A
FOSL1 FOS-like antigen 1
GLUL glutamate-ammonia ligase
GPRC5A G protein-coupled receptor, class C, group 5, member A
HIST1H2BK histone cluster 1, H2bk
HMOX1 heme oxygenase 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPH1 heat shock 105kDa/110kDa protein 1
IDE insulin-degrading enzyme
IER5 immediate early response 5
MDFIC MyoD family inhibitor domain containing
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
NCK2 NCK adaptor protein 2
NELL2 NEL-like 2 (chicken)
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PMP22 peripheral myelin protein 22
PNP purine nucleoside phosphorylase
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
RNMT RNA (guanine-7-) methyltransferase
SRGN serglycin
ST7 suppression of tumorigenicity 7
STIP1 stress-induced phosphoprotein 1
THBS4 thrombospondin 4

decreased expression

Symbol Name
ACAT2 acetyl-CoA acetyltransferase 2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
AOX1 aldehyde oxidase 1
CCL20 chemokine (C-C motif) ligand 20
CCNA2 cyclin A2
CCND1 cyclin D1
CD200 CD200 molecule
CD24 CD24 molecule
CDC20 cell division cycle 20
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
COCH cochlin
CXCL2 chemokine (C-X-C motif) ligand 2
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FGG fibrinogen gamma chain
FST follistatin
GDF15 growth differentiation factor 15
GPX2 glutathione peroxidase 2
GREB1 growth regulation by estrogen in breast cancer 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP4 insulin-like growth factor binding protein 4
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
LOXL1 lysyl oxidase-like 1
LPAR6 lysophosphatidic acid receptor 6
MFAP5 microfibrillar associated protein 5
MSMB microseminoprotein, beta-
MTSS1 metastasis suppressor 1
MYCBP MYC binding protein
NIPSNAP1 nipsnap homolog 1 (C. elegans)
NSDHL NAD(P) dependent steroid dehydrogenase-like
NUPR1 nuclear protein, transcriptional regulator, 1
PCP4 Purkinje cell protein 4
PLA1A phospholipase A1 member A
PLAGL1 pleiomorphic adenoma gene-like 1
PLCB4 phospholipase C, beta 4
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
RNASE4 ribonuclease, RNase A family, 4
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SORD sorbitol dehydrogenase
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10