BRD-A20697603_T8902_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

80 genes differentially expressed following the BRD-A20697603_T8902_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BAG3 BCL2-associated athanogene 3
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CKB creatine kinase, brain
CLU clusterin
CSRP2 cysteine and glycine-rich protein 2
CTH cystathionine gamma-lyase
CXCL14 chemokine (C-X-C motif) ligand 14
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
FADS1 fatty acid desaturase 1
FAM107A family with sequence similarity 107, member A
FKBP11 FK506 binding protein 11, 19 kDa
FKBP14 FK506 binding protein 14, 22 kDa
FOSL1 FOS-like antigen 1
FTH1 ferritin, heavy polypeptide 1
GLRX glutaredoxin (thioltransferase)
GPM6B glycoprotein M6B
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA13 heat shock protein 70kDa family, member 13
HSPA1A heat shock 70kDa protein 1A
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
IDI1 isopentenyl-diphosphate delta isomerase 1
IER5 immediate early response 5
IFRD1 interferon-related developmental regulator 1
INSIG1 insulin induced gene 1
JMJD6 jumonji domain containing 6
KCTD5 potassium channel tetramerization domain containing 5
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MICB MHC class I polypeptide-related sequence B
MLF1 myeloid leukemia factor 1
MSMO1 methylsterol monooxygenase 1
MT1F metallothionein 1F
MT1M metallothionein 1M
NSDHL NAD(P) dependent steroid dehydrogenase-like
NUCB2 nucleobindin 2
PLIN2 perilipin 2
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPAP2B phosphatidic acid phosphatase type 2B
SCGB2A1 secretoglobin, family 2A, member 1
SDF2L1 stromal cell-derived factor 2-like 1
SERP1 stress-associated endoplasmic reticulum protein 1
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SQLE squalene epoxidase
SQSTM1 sequestosome 1
UGDH UDP-glucose 6-dehydrogenase
WBP5 WW domain binding protein 5
WIF1 WNT inhibitory factor 1
WIPI1 WD repeat domain, phosphoinositide interacting 1

decreased expression

Symbol Name
ACTA2 actin, alpha 2, smooth muscle, aorta
AREG amphiregulin
BMP4 bone morphogenetic protein 4
CCL4 chemokine (C-C motif) ligand 4
FBP1 fructose-1,6-bisphosphatase 1
FXYD5 FXYD domain containing ion transport regulator 5
GATA2 GATA binding protein 2
GBP1 guanylate binding protein 1, interferon-inducible
GOLGA8A golgin A8 family, member A
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
IL1RN interleukin 1 receptor antagonist
KRT7 keratin 7, type II
NRN1 neuritin 1
PBX1 pre-B-cell leukemia homeobox 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
S100A9 S100 calcium binding protein A9
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
TGFB1 transforming growth factor, beta 1
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TM4SF4 transmembrane 4 L six family member 4
TMEM5 transmembrane protein 5