BRD-A20697603_T8902_HCC515_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

80 genes differentially expressed following the BRD-A20697603_T8902_HCC515_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ACTG2 actin, gamma 2, smooth muscle, enteric
AQP3 aquaporin 3 (Gill blood group)
BAG3 BCL2-associated athanogene 3
CA2 carbonic anhydrase II
CD40 CD40 molecule, TNF receptor superfamily member 5
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CLU clusterin
CSRP1 cysteine and glycine-rich protein 1
DEFA4 defensin, alpha 4, corticostatin
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EGFR epidermal growth factor receptor
EPAS1 endothelial PAS domain protein 1
FAM46A family with sequence similarity 46, member A
GPNMB glycoprotein (transmembrane) nmb
GSN gelsolin
GSTA1 glutathione S-transferase alpha 1
GUSBP11 glucuronidase, beta pseudogene 11
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMOX1 heme oxygenase 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA1A heat shock 70kDa protein 1A
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPH1 heat shock 105kDa/110kDa protein 1
IDI1 isopentenyl-diphosphate delta isomerase 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGHM immunoglobulin heavy constant mu
IGKV1-5 immunoglobulin kappa variable 1-5
IGLV2-23 immunoglobulin lambda variable 2-23
JMJD6 jumonji domain containing 6
LTF lactotransferrin
MAN1A1 mannosidase, alpha, class 1A, member 1
MAOB monoamine oxidase B
METTL7A methyltransferase like 7A
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MSMO1 methylsterol monooxygenase 1
MYH11 myosin, heavy chain 11, smooth muscle
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
NRIP1 nuclear receptor interacting protein 1
POU2AF1 POU class 2 associating factor 1
PPAP2B phosphatidic acid phosphatase type 2B
RYBP RING1 and YY1 binding protein
S100P S100 calcium binding protein P
SAT1 spermidine/spermine N1-acetyltransferase 1
SC5D sterol-C5-desaturase
SEPP1 selenoprotein P, plasma, 1
SPARCL1 SPARC-like 1 (hevin)
TCTA T-cell leukemia translocation altered
TIMP3 TIMP metallopeptidase inhibitor 3
TUBB2A tubulin, beta 2A class IIa

decreased expression

Symbol Name
ABLIM1 actin binding LIM protein 1
AHNAK2 AHNAK nucleoprotein 2
BHLHE40 basic helix-loop-helix family, member e40
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
DDB2 damage-specific DNA binding protein 2, 48kDa
FGFR3 fibroblast growth factor receptor 3
FLG filaggrin
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GSTM3 glutathione S-transferase mu 3 (brain)
IL1RAP interleukin 1 receptor accessory protein
KRCC1 lysine-rich coiled-coil 1
KRT7 keratin 7, type II
NLRP2 NLR family, pyrin domain containing 2
PLAGL1 pleiomorphic adenoma gene-like 1
PLS1 plastin 1
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
RBP1 retinol binding protein 1, cellular
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
TFPI2 tissue factor pathway inhibitor 2
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TSPAN4 tetraspanin 4
VCAN versican