BRD-A20697603_T8902_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

185 genes differentially expressed following the BRD-A20697603_T8902_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
ADM adrenomedullin
AKAP13 A kinase (PRKA) anchor protein 13
ARID4B AT rich interactive domain 4B (RBP1-like)
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
BAG3 BCL2-associated athanogene 3
BAMBI BMP and activin membrane-bound inhibitor
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CD163 CD163 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDK17 cyclin-dependent kinase 17
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
CECR1 cat eye syndrome chromosome region, candidate 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CKS2 CDC28 protein kinase regulatory subunit 2
CLIC4 chloride intracellular channel 4
CLU clusterin
COBL cordon-bleu WH2 repeat protein
CPM carboxypeptidase M
CSRP1 cysteine and glycine-rich protein 1
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DSG3 desmoglein 3
DUSP1 dual specificity phosphatase 1
DUSP2 dual specificity phosphatase 2
ELANE elastase, neutrophil expressed
ELOVL4 ELOVL fatty acid elongase 4
ENOPH1 enolase-phosphatase 1
ESR1 estrogen receptor 1
FAM46C family with sequence similarity 46, member C
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXG1 forkhead box G1
GFOD1 glucose-fructose oxidoreductase domain containing 1
GLRX glutaredoxin (thioltransferase)
GLUL glutamate-ammonia ligase
GUSBP11 glucuronidase, beta pseudogene 11
GUSBP3 glucuronidase, beta pseudogene 3
HEBP2 heme binding protein 2
HECA headcase homolog (Drosophila)
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H2BG histone cluster 1, H2bg
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HSPA13 heat shock protein 70kDa family, member 13
HSPA1A heat shock 70kDa protein 1A
HSPA2 heat shock 70kDa protein 2
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPB8 heat shock 22kDa protein 8
HSPH1 heat shock 105kDa/110kDa protein 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IDI1 isopentenyl-diphosphate delta isomerase 1
IFRD1 interferon-related developmental regulator 1
IL1R1 interleukin 1 receptor, type I
INSIG1 insulin induced gene 1
IRF8 interferon regulatory factor 8
KLHL21 kelch-like family member 21
LGALS8 lectin, galactoside-binding, soluble, 8
LRMP lymphoid-restricted membrane protein
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP7 microtubule-associated protein 7
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MMP9 matrix metallopeptidase 9
NPTX2 neuronal pentraxin II
NSFL1C NSFL1 (p97) cofactor (p47)
NUPL1 nucleoporin like 1
PELI1 pellino E3 ubiquitin protein ligase 1
PERP PERP, TP53 apoptosis effector
PHACTR2 phosphatase and actin regulator 2
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PSAP prosaposin
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
PTPRO protein tyrosine phosphatase, receptor type, O
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RGCC regulator of cell cycle
RYBP RING1 and YY1 binding protein
S100A8 S100 calcium binding protein A8
S100P S100 calcium binding protein P
SAT1 spermidine/spermine N1-acetyltransferase 1
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SELENBP1 selenium binding protein 1
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC38A2 solute carrier family 38, member 2
SPINT1 serine peptidase inhibitor, Kunitz type 1
SST somatostatin
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
SUCO SUN domain containing ossification factor
TMEM30B transmembrane protein 30B
TMSB15A thymosin beta 15a
TRA2A transformer 2 alpha homolog (Drosophila)
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
TRIB3 tribbles pseudokinase 3
TSC22D3 TSC22 domain family, member 3
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
TYROBP TYRO protein tyrosine kinase binding protein
WIF1 WNT inhibitory factor 1

decreased expression

Symbol Name
ACP6 acid phosphatase 6, lysophosphatidic
ACSL5 acyl-CoA synthetase long-chain family member 5
ACTA2 actin, alpha 2, smooth muscle, aorta
AK4 adenylate kinase 4
ALCAM activated leukocyte cell adhesion molecule
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AMZ2 archaelysin family metallopeptidase 2
ANKRD10 ankyrin repeat domain 10
ANXA6 annexin A6
BAX BCL2-associated X protein
BBS1 Bardet-Biedl syndrome 1
BHLHE40 basic helix-loop-helix family, member e40
BST2 bone marrow stromal cell antigen 2
CASP7 caspase 7, apoptosis-related cysteine peptidase
CBR3 carbonyl reductase 3
CCDC92 coiled-coil domain containing 92
CCND1 cyclin D1
CCNF cyclin F
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CHMP6 charged multivesicular body protein 6
COA3 cytochrome c oxidase assembly factor 3
COASY CoA synthase
COL5A1 collagen, type V, alpha 1
CTBP1 C-terminal binding protein 1
DDB2 damage-specific DNA binding protein 2, 48kDa
DFNA5 deafness, autosomal dominant 5
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EIF5A eukaryotic translation initiation factor 5A
FKBP10 FK506 binding protein 10, 65 kDa
FZD2 frizzled class receptor 2
FZD7 frizzled class receptor 7
GAS1 growth arrest-specific 1
GOLGA8A golgin A8 family, member A
GOLGA8B golgin A8 family, member B
GSTM3 glutathione S-transferase mu 3 (brain)
HOXC10 homeobox C10
HOXC6 homeobox C6
IGFBP4 insulin-like growth factor binding protein 4
JADE2 jade family PHD finger 2
LOXL1 lysyl oxidase-like 1
LRRN3 leucine rich repeat neuronal 3
LUM lumican
MAGEA3 melanoma antigen family A3
MMP12 matrix metallopeptidase 12
MTA1 metastasis associated 1
NR2F1 nuclear receptor subfamily 2, group F, member 1
OXLD1 oxidoreductase-like domain containing 1
OXTR oxytocin receptor
PAX8 paired box 8
PBX3 pre-B-cell leukemia homeobox 3
PCYOX1L prenylcysteine oxidase 1 like
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PLAC8 placenta-specific 8
PLAT plasminogen activator, tissue
PLK1 polo-like kinase 1
PNMA2 paraneoplastic Ma antigen 2
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
POLG2 polymerase (DNA directed), gamma 2, accessory subunit
POSTN periostin, osteoblast specific factor
PRKCA protein kinase C, alpha
PRR7 proline rich 7 (synaptic)
PTGES prostaglandin E synthase
RHOBTB3 Rho-related BTB domain containing 3
S100A2 S100 calcium binding protein A2
SMAD3 SMAD family member 3
STXBP1 syntaxin binding protein 1
SULF1 sulfatase 1
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
TGM2 transglutaminase 2
THBS1 thrombospondin 1
TNS1 tensin 1
TNS3 tensin 3
TYRP1 tyrosinase-related protein 1
UBE3C ubiquitin protein ligase E3C
ZNF580 zinc finger protein 580