BRD-A20697603_598226_PHH_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

109 genes differentially expressed following the BRD-A20697603_598226_PHH_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
BAG3 BCL2-associated athanogene 3
C16ORF45 chromosome 16 open reading frame 45
CAV1 caveolin 1, caveolae protein, 22kDa
CBR3 carbonyl reductase 3
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CSRP1 cysteine and glycine-rich protein 1
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
FAM46A family with sequence similarity 46, member A
FKBP14 FK506 binding protein 14, 22 kDa
FOSL1 FOS-like antigen 1
GLRX glutaredoxin (thioltransferase)
HBB hemoglobin, beta
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPH1 heat shock 105kDa/110kDa protein 1
IL7R interleukin 7 receptor
JMJD6 jumonji domain containing 6
KIF14 kinesin family member 14
LPPR4 lipid phosphate phosphatase-related protein type 4
LYPD1 LY6/PLAUR domain containing 1
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MECOM MDS1 and EVI1 complex locus
MICB MHC class I polypeptide-related sequence B
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit
NOTCH2NL notch 2 N-terminal like
PBX3 pre-B-cell leukemia homeobox 3
PCDH9 protocadherin 9
PDZD2 PDZ domain containing 2
PNP purine nucleoside phosphorylase
PRKCA protein kinase C, alpha
SFRP4 secreted frizzled-related protein 4
SH3YL1 SH3 and SYLF domain containing 1
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TEX10 testis expressed 10
TGFBI transforming growth factor, beta-induced, 68kDa
WLS wntless Wnt ligand secretion mediator
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
ALCAM activated leukocyte cell adhesion molecule
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
APOC1 apolipoprotein C-I
BEX1 brain expressed, X-linked 1
BTG2 BTG family, member 2
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CCL20 chemokine (C-C motif) ligand 20
CCNA2 cyclin A2
CCND1 cyclin D1
CD24 CD24 molecule
CDC20 cell division cycle 20
CELF2 CUGBP, Elav-like family member 2
CFB complement factor B
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
CRYAB crystallin, alpha B
CTSH cathepsin H
CXCL2 chemokine (C-X-C motif) ligand 2
DKK3 dickkopf WNT signaling pathway inhibitor 3
DLK1 delta-like 1 homolog (Drosophila)
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ERLIN2 ER lipid raft associated 2
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FBN1 fibrillin 1
FGF13 fibroblast growth factor 13
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLF hepatic leukemia factor
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
JCHAIN joining chain of multimeric IgA and IgM
LOXL1 lysyl oxidase-like 1
MEF2C myocyte enhancer factor 2C
MFAP5 microfibrillar associated protein 5
NDN necdin, melanoma antigen (MAGE) family member
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NOV nephroblastoma overexpressed
NPY1R neuropeptide Y receptor Y1
NT5DC2 5'-nucleotidase domain containing 2
PARP2 poly (ADP-ribose) polymerase 2
PDGFC platelet derived growth factor C
PLAGL1 pleiomorphic adenoma gene-like 1
PNMA2 paraneoplastic Ma antigen 2
PXMP2 peroxisomal membrane protein 2, 22kDa
QKI QKI, KH domain containing, RNA binding
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RELN reelin
RGS1 regulator of G-protein signaling 1
RGS13 regulator of G-protein signaling 13
SFRP1 secreted frizzled-related protein 1
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SQRDL sulfide quinone reductase-like (yeast)
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNS3 tensin 3
TOX thymocyte selection-associated high mobility group box
TYMS thymidylate synthetase
VCAM1 vascular cell adhesion molecule 1
VCAN versican