BRD-A20697603_598226_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

210 genes differentially expressed following the BRD-A20697603_598226_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRF5 adhesion G protein-coupled receptor F5
ADGRL4 adhesion G protein-coupled receptor L4
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ALB albumin
AQP1 aquaporin 1 (Colton blood group)
ARMCX2 armadillo repeat containing, X-linked 2
ASPN asporin
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
BEX4 brain expressed, X-linked 4
BLNK B-cell linker
C3ORF14 chromosome 3 open reading frame 14
CADM1 cell adhesion molecule 1
CD93 CD93 molecule
CECR1 cat eye syndrome chromosome region, candidate 1
CHGB chromogranin B
CLC Charcot-Leyden crystal galectin
COBLL1 cordon-bleu WH2 repeat protein-like 1
COL11A1 collagen, type XI, alpha 1
CP ceruloplasmin (ferroxidase)
CPE carboxypeptidase E
CPM carboxypeptidase M
CXCL9 chemokine (C-X-C motif) ligand 9
DCN decorin
DDIT4 DNA-damage-inducible transcript 4
DIO1 deiodinase, iodothyronine, type I
DOK5 docking protein 5
DUSP1 dual specificity phosphatase 1
EFHD1 EF-hand domain family, member D1
EGFL6 EGF-like-domain, multiple 6
EIF1 eukaryotic translation initiation factor 1
EPAS1 endothelial PAS domain protein 1
ERBB4 erb-b2 receptor tyrosine kinase 4
FN1 fibronectin 1
FOS FBJ murine osteosarcoma viral oncogene homolog
GADD45B growth arrest and DNA-damage-inducible, beta
GLUL glutamate-ammonia ligase
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GPRASP1 G protein-coupled receptor associated sorting protein 1
HBB hemoglobin, beta
HHEX hematopoietically expressed homeobox
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGFBP5 insulin-like growth factor binding protein 5
IL1R1 interleukin 1 receptor, type I
INA internexin neuronal intermediate filament protein, alpha
ISYNA1 inositol-3-phosphate synthase 1
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KLF9 Kruppel-like factor 9
LGALS8 lectin, galactoside-binding, soluble, 8
LST1 leukocyte specific transcript 1
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1M metallothionein 1M
MXRA5 matrix-remodelling associated 5
ORM1 orosomucoid 1
PBX3 pre-B-cell leukemia homeobox 3
PEG3 paternally expressed 3
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLEKHO1 pleckstrin homology domain containing, family O member 1
PLVAP plasmalemma vesicle associated protein
PON3 paraoxonase 3
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RGS16 regulator of G-protein signaling 16
RGS5 regulator of G-protein signaling 5
RSU1 Ras suppressor protein 1
SCG5 secretogranin V
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SEPP1 selenoprotein P, plasma, 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SOX17 SRY (sex determining region Y)-box 17
SPINK1 serine peptidase inhibitor, Kazal type 1
SST somatostatin
STC1 stanniocalcin 1
STMN2 stathmin 2
SULF1 sulfatase 1
UGP2 UDP-glucose pyrophosphorylase 2
VTCN1 V-set domain containing T cell activation inhibitor 1
XIST X inactive specific transcript (non-protein coding)
ZFPM2 zinc finger protein, FOG family member 2
ZNF117 zinc finger protein 117
ZNF331 zinc finger protein 331
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
ADO 2-aminoethanethiol (cysteamine) dioxygenase
ADORA2B adenosine A2b receptor
AK1 adenylate kinase 1
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANXA3 annexin A3
ANXA7 annexin A7
AQP3 aquaporin 3 (Gill blood group)
ARFIP2 ADP-ribosylation factor interacting protein 2
ATPIF1 ATPase inhibitory factor 1
B3GNT1
CBR3 carbonyl reductase 3
CCNA2 cyclin A2
CCNB2 cyclin B2
CCND1 cyclin D1
CDA cytidine deaminase
CDC20 cell division cycle 20
CDC25A cell division cycle 25A
CDC25B cell division cycle 25B
CDCA4 cell division cycle associated 4
CDK1 cyclin-dependent kinase 1
CDKN3 cyclin-dependent kinase inhibitor 3
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHERP calcium homeostasis endoplasmic reticulum protein
COMMD4 COMM domain containing 4
CST6 cystatin E/M
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DUSP4 dual specificity phosphatase 4
ECD ecdysoneless homolog (Drosophila)
EFNB2 ephrin-B2
EIF5A eukaryotic translation initiation factor 5A
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
FOSL1 FOS-like antigen 1
FSTL1 follistatin-like 1
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7
GAS1 growth arrest-specific 1
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GSTP1 glutathione S-transferase pi 1
HDAC1 histone deacetylase 1
HN1 hematological and neurological expressed 1
HOXA10 homeobox A10
HOXB7 homeobox B7
IGFBP6 insulin-like growth factor binding protein 6
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1
ITGA6 integrin, alpha 6
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIF20A kinesin family member 20A
KPNB1 karyopherin (importin) beta 1
KRT10 keratin 10, type I
KRT14 keratin 14, type I
KRT15 keratin 15, type I
KRT17 keratin 17, type I
LAMA3 laminin, alpha 3
LAMB3 laminin, beta 3
LIMCH1 LIM and calponin homology domains 1
MALL mal, T-cell differentiation protein-like
MET MET proto-oncogene, receptor tyrosine kinase
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MRPS30 mitochondrial ribosomal protein S30
NBN nibrin
NKX3-1 NK3 homeobox 1
NQO1 NAD(P)H dehydrogenase, quinone 1
NUP62 nucleoporin 62kDa
NUP85 nucleoporin 85kDa
PARP2 poly (ADP-ribose) polymerase 2
PAX2 paired box 2
PCNA proliferating cell nuclear antigen
PDLIM4 PDZ and LIM domain 4
PFKP phosphofructokinase, platelet
PHB prohibitin
PI3 peptidase inhibitor 3, skin-derived
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PIP prolactin-induced protein
PKM pyruvate kinase, muscle
PKP1 plakophilin 1
PNP purine nucleoside phosphorylase
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PPAP2C phosphatidic acid phosphatase type 2C
PRKCD protein kinase C, delta
PRMT1 protein arginine methyltransferase 1
PRSS3 protease, serine, 3
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PSPH phosphoserine phosphatase
RBBP4 retinoblastoma binding protein 4
RFC2 replication factor C (activator 1) 2, 40kDa
RPL36AL ribosomal protein L36a-like
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
S100A2 S100 calcium binding protein A2
S100A7 S100 calcium binding protein A7
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC35B1 solute carrier family 35, member B1
SLIRP SRA stem-loop interacting RNA binding protein
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa
SOX9 SRY (sex determining region Y)-box 9
SPOP speckle-type POZ protein
SPRR1A small proline-rich protein 1A
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TMEM5 transmembrane protein 5
TMX1 thioredoxin-related transmembrane protein 1
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TRAPPC3 trafficking protein particle complex 3
TRIM16 tripartite motif containing 16
TSPAN8 tetraspanin 8
TWF2 twinfilin actin binding protein 2
TXLNA taxilin alpha
TYMS thymidylate synthetase
UBE2C ubiquitin-conjugating enzyme E2C
UBE2S ubiquitin-conjugating enzyme E2S
UBE3C ubiquitin protein ligase E3C
USP22 ubiquitin specific peptidase 22
YBX3 Y box binding protein 3
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF185 zinc finger protein 185 (LIM domain)