BRD-A20697603_598226_NEU_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

151 genes differentially expressed following the BRD-A20697603_598226_NEU_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANXA1 annexin A1
AQP3 aquaporin 3 (Gill blood group)
ASS1 argininosuccinate synthase 1
ATAD2 ATPase family, AAA domain containing 2
BAG3 BCL2-associated athanogene 3
CAV1 caveolin 1, caveolae protein, 22kDa
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
CRISP3 cysteine-rich secretory protein 3
CSRP1 cysteine and glycine-rich protein 1
CTSZ cathepsin Z
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL8 chemokine (C-X-C motif) ligand 8
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DSP desmoplakin
DUSP6 dual specificity phosphatase 6
EGR1 early growth response 1
EMP1 epithelial membrane protein 1
ESR1 estrogen receptor 1
FKBP11 FK506 binding protein 11, 19 kDa
G0S2 G0/G1 switch 2
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GEM GTP binding protein overexpressed in skeletal muscle
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GPR88 G protein-coupled receptor 88
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPB1 heat shock 27kDa protein 1
HSPH1 heat shock 105kDa/110kDa protein 1
IFRD1 interferon-related developmental regulator 1
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV4-1 immunoglobulin kappa variable 4-1
IGLV2-23 immunoglobulin lambda variable 2-23
JCHAIN joining chain of multimeric IgA and IgM
KIF14 kinesin family member 14
KRT19 keratin 19, type I
KRT4 keratin 4, type II
LCN2 lipocalin 2
LINC00341 long intergenic non-protein coding RNA 341
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP2K3 mitogen-activated protein kinase kinase 3
MMP9 matrix metallopeptidase 9
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
NET1 neuroepithelial cell transforming 1
PDGFA platelet-derived growth factor alpha polypeptide
PERP PERP, TP53 apoptosis effector
PPL periplakin
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
S100A10 S100 calcium binding protein A10
S100A7 S100 calcium binding protein A7
S100A9 S100 calcium binding protein A9
SOD2 superoxide dismutase 2, mitochondrial
SPRR3 small proline-rich protein 3
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TPBG trophoblast glycoprotein
TPD52 tumor protein D52
TPD52L1 tumor protein D52-like 1
TWIST1 twist family bHLH transcription factor 1
ZFAND5 zinc finger, AN1-type domain 5

decreased expression

Symbol Name
ACTC1 actin, alpha, cardiac muscle 1
ADCY1 adenylate cyclase 1 (brain)
ADO 2-aminoethanethiol (cysteamine) dioxygenase
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALCAM activated leukocyte cell adhesion molecule
BASP1 brain abundant, membrane attached signal protein 1
BEX1 brain expressed, X-linked 1
BTBD3 BTB (POZ) domain containing 3
CADM1 cell adhesion molecule 1
CCNI cyclin I
CDC20 cell division cycle 20
CDK4 cyclin-dependent kinase 4
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CIRBP cold inducible RNA binding protein
CKB creatine kinase, brain
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family)
CYFIP2 cytoplasmic FMR1 interacting protein 2
DES desmin
DPYSL3 dihydropyrimidinase-like 3
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha)
EPHA3 EPH receptor A3
EPHB2 EPH receptor B2
FABP7 fatty acid binding protein 7, brain
FADS1 fatty acid desaturase 1
FAM134A family with sequence similarity 134, member A
FAM171A1 family with sequence similarity 171, member A1
FGF13 fibroblast growth factor 13
FOXN3 forkhead box N3
FZD7 frizzled class receptor 7
GALC galactosylceramidase
GPX1 glutathione peroxidase 1
GSTP1 glutathione S-transferase pi 1
HBB hemoglobin, beta
HOXB7 homeobox B7
MAB21L2 mab-21-like 2 (C. elegans)
MAGED1 melanoma antigen family D1
MAP1B microtubule-associated protein 1B
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MARCKSL1 MARCKS-like 1
MET MET proto-oncogene, receptor tyrosine kinase
MFAP5 microfibrillar associated protein 5
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NIPSNAP1 nipsnap homolog 1 (C. elegans)
NREP neuronal regeneration related protein
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PLAGL1 pleiomorphic adenoma gene-like 1
PLCB4 phospholipase C, beta 4
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PRDX2 peroxiredoxin 2
PROM1 prominin 1
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
PTPRD protein tyrosine phosphatase, receptor type, D
PXDN peroxidasin
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
REEP1 receptor accessory protein 1
RPS4Y1 ribosomal protein S4, Y-linked 1
SCAND1 SCAN domain containing 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SIDT2 SID1 transmembrane family, member 2
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SOX4 SRY (sex determining region Y)-box 4
STK25 serine/threonine kinase 25
STMN2 stathmin 2
STXBP1 syntaxin binding protein 1
SYT1 synaptotagmin I
TCAF1 TRPM8 channel-associated factor 1
TGFBI transforming growth factor, beta-induced, 68kDa
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast)
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TLE4 transducin-like enhancer of split 4
TOX3 TOX high mobility group box family member 3
TUBB tubulin, beta class I
VAT1 vesicle amine transport 1
VCAN versican
WDR13 WD repeat domain 13
ZBTB18 zinc finger and BTB domain containing 18
ZFPM2 zinc finger protein, FOG family member 2
ZMYND8 zinc finger, MYND-type containing 8