BRD-A20697603_598226_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

151 genes differentially expressed following the BRD-A20697603_598226_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARMCX1 armadillo repeat containing, X-linked 1
ATF3 activating transcription factor 3
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
BASP1 brain abundant, membrane attached signal protein 1
BCL3 B-cell CLL/lymphoma 3
BIRC3 baculoviral IAP repeat containing 3
BMP2 bone morphogenetic protein 2
CCL20 chemokine (C-C motif) ligand 20
CD9 CD9 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CETN2 centrin, EF-hand protein, 2
CLU clusterin
CPM carboxypeptidase M
CRIP1 cysteine-rich protein 1 (intestinal)
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DUSP5 dual specificity phosphatase 5
EPAS1 endothelial PAS domain protein 1
EPHA3 EPH receptor A3
EZR ezrin
F2RL1 coagulation factor II (thrombin) receptor-like 1
FADS1 fatty acid desaturase 1
FAM129A family with sequence similarity 129, member A
FHL1 four and a half LIM domains 1
FOS FBJ murine osteosarcoma viral oncogene homolog
GABARAPL1 GABA(A) receptor-associated protein like 1
GDI1 GDP dissociation inhibitor 1
GEM GTP binding protein overexpressed in skeletal muscle
GLRX glutaredoxin (thioltransferase)
GOLT1B golgi transport 1B
HBEGF heparin-binding EGF-like growth factor
HBP1 HMG-box transcription factor 1
HIST1H1C histone cluster 1, H1c
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HPSE heparanase
HSPA13 heat shock protein 70kDa family, member 13
ICAM1 intercellular adhesion molecule 1
IDI1 isopentenyl-diphosphate delta isomerase 1
IDS iduronate 2-sulfatase
IER3 immediate early response 3
IL1A interleukin 1, alpha
IL32 interleukin 32
IL7R interleukin 7 receptor
INSIG1 insulin induced gene 1
IQCG IQ motif containing G
IRF1 interferon regulatory factor 1
ISG20 interferon stimulated exonuclease gene 20kDa
JAG1 jagged 1
KLF4 Kruppel-like factor 4 (gut)
KLF6 Kruppel-like factor 6
LARP6 La ribonucleoprotein domain family, member 6
LDLR low density lipoprotein receptor
LTB lymphotoxin beta (TNF superfamily, member 3)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MIR22HG MIR22 host gene
MLF1 myeloid leukemia factor 1
MSMB microseminoprotein, beta-
MSMO1 methylsterol monooxygenase 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NR4A3 nuclear receptor subfamily 4, group A, member 3
NSDHL NAD(P) dependent steroid dehydrogenase-like
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUCB2 nucleobindin 2
OPTN optineurin
PHLDA1 pleckstrin homology-like domain, family A, member 1
PPAP2B phosphatidic acid phosphatase type 2B
PPP1R15A protein phosphatase 1, regulatory subunit 15A
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
SDC4 syndecan 4
SFN stratifin
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMAD3 SMAD family member 3
SOD2 superoxide dismutase 2, mitochondrial
STC1 stanniocalcin 1
TMEM41B transmembrane protein 41B
TMSB15A thymosin beta 15a
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNIP1 TNFAIP3 interacting protein 1
TUBB2A tubulin, beta 2A class IIa
TUFT1 tuftelin 1
VEGFA vascular endothelial growth factor A
VNN1 vanin 1
XBP1 X-box binding protein 1

decreased expression

Symbol Name
ANAPC1 anaphase promoting complex subunit 1
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
ATR ATR serine/threonine kinase
AURKA aurora kinase A
BMP4 bone morphogenetic protein 4
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CCNA2 cyclin A2
CDC20 cell division cycle 20
CDC25B cell division cycle 25B
CDKN3 cyclin-dependent kinase inhibitor 3
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CENPA centromere protein A
CX3CR1 chemokine (C-X3-C motif) receptor 1
DCPS decapping enzyme, scavenger
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DPH2 DPH2 homolog (S. cerevisiae)
F12 coagulation factor XII (Hageman factor)
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM216A family with sequence similarity 216, member A
GATA2 GATA binding protein 2
GNAS GNAS complex locus
GOLGA8A golgin A8 family, member A
GOLGA8H golgin A8 family, member H
GRIA2 glutamate receptor, ionotropic, AMPA 2
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HMMR hyaluronan-mediated motility receptor (RHAMM)
HOXC6 homeobox C6
ICMT isoprenylcysteine carboxyl methyltransferase
JADE2 jade family PHD finger 2
KIF20A kinesin family member 20A
LAMA4 laminin, alpha 4
MAP2K6 mitogen-activated protein kinase kinase 6
MGST2 microsomal glutathione S-transferase 2
MKI67 marker of proliferation Ki-67
NDN necdin, melanoma antigen (MAGE) family member
NR2F2 nuclear receptor subfamily 2, group F, member 2
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLAC8 placenta-specific 8
PLK1 polo-like kinase 1
PTCH1 patched 1
PURA purine-rich element binding protein A
RGS2 regulator of G-protein signaling 2
RHOBTB3 Rho-related BTB domain containing 3
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPDL1 spindle apparatus coiled-coil protein 1
SPON2 spondin 2, extracellular matrix protein
TARBP1 TAR (HIV-1) RNA binding protein 1
TBC1D4 TBC1 domain family, member 4
TBC1D9B TBC1 domain family, member 9B (with GRAM domain)
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMEM5 transmembrane protein 5
TNC tenascin C
TSEN2 TSEN2 tRNA splicing endonuclease subunit
UBE2S ubiquitin-conjugating enzyme E2S
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
ZW10 zw10 kinetochore protein