BRD-A20697603_598226_A549_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

120 genes differentially expressed following the BRD-A20697603_598226_A549_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACAA2 acetyl-CoA acyltransferase 2
ANG angiogenin, ribonuclease, RNase A family, 5
APOD apolipoprotein D
ARG2 arginase 2
ATF3 activating transcription factor 3
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BEX1 brain expressed, X-linked 1
BEX4 brain expressed, X-linked 4
BZW2 basic leucine zipper and W2 domains 2
CD24 CD24 molecule
CD59 CD59 molecule, complement regulatory protein
CLDN3 claudin 3
CLIC3 chloride intracellular channel 3
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
CRIP2 cysteine-rich protein 2
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
CYTIP cytohesin 1 interacting protein
DCN decorin
DCTN1 dynactin 1
DDIT4 DNA-damage-inducible transcript 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DPT dermatopontin
DSP desmoplakin
EPB41L3 erythrocyte membrane protein band 4.1-like 3
FAM49A family with sequence similarity 49, member A
FGL2 fibrinogen-like 2
GARS glycyl-tRNA synthetase
GNAS GNAS complex locus
HBP1 HMG-box transcription factor 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HOPX HOP homeobox
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPB8 heat shock 22kDa protein 8
IDI1 isopentenyl-diphosphate delta isomerase 1
INSIG1 insulin induced gene 1
JUND jun D proto-oncogene
KLHL24 kelch-like family member 24
KRT14 keratin 14, type I
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
LDLR low density lipoprotein receptor
LXN latexin
LYPD3 LY6/PLAUR domain containing 3
MAGEA3 melanoma antigen family A3
MAP7 microtubule-associated protein 7
MB myoglobin
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
METTL7A methyltransferase like 7A
MSMO1 methylsterol monooxygenase 1
NDRG1 N-myc downstream regulated 1
NEBL nebulette
NPY1R neuropeptide Y receptor Y1
NSDHL NAD(P) dependent steroid dehydrogenase-like
NUPR1 nuclear protein, transcriptional regulator, 1
PAWR PRKC, apoptosis, WT1, regulator
PPL periplakin
PSAP prosaposin
RAP1GAP2 RAP1 GTPase activating protein 2
REEP1 receptor accessory protein 1
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RNF167 ring finger protein 167
RTN1 reticulon 1
S100A14 S100 calcium binding protein A14
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SFN stratifin
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
STX1A syntaxin 1A (brain)
TACSTD2 tumor-associated calcium signal transducer 2
TAGLN2 transgelin 2
TCEAL2 transcription elongation factor A (SII)-like 2
TSC22D3 TSC22 domain family, member 3
TSPAN13 tetraspanin 13
TUFT1 tuftelin 1
VAT1 vesicle amine transport 1
XBP1 X-box binding protein 1

decreased expression

Symbol Name
ANKRD36B ankyrin repeat domain 36B
AZU1 azurocidin 1
BRCA1 breast cancer 1, early onset
CCL2 chemokine (C-C motif) ligand 2
CCND1 cyclin D1
CDCA3 cell division cycle associated 3
COL6A1 collagen, type VI, alpha 1
CP ceruloplasmin (ferroxidase)
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL8 chemokine (C-X-C motif) ligand 8
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
EGFR epidermal growth factor receptor
ELN elastin
FOSL1 FOS-like antigen 1
FST follistatin
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2
HMMR hyaluronan-mediated motility receptor (RHAMM)
IGFBP1 insulin-like growth factor binding protein 1
IGFBP3 insulin-like growth factor binding protein 3
IRS1 insulin receptor substrate 1
KIF20A kinesin family member 20A
MX1 MX dynamin-like GTPase 1
MX2 MX dynamin-like GTPase 2
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLAC8 placenta-specific 8
PRKCA protein kinase C, alpha
PSPH phosphoserine phosphatase
RGS2 regulator of G-protein signaling 2
SOX11 SRY (sex determining region Y)-box 11
TFPI2 tissue factor pathway inhibitor 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TSEN2 TSEN2 tRNA splicing endonuclease subunit
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
WT1 Wilms tumor 1