BRD-A20348246_Chlormezanone_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

54 genes differentially expressed following the BRD-A20348246_Chlormezanone_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRG6 adhesion G protein-coupled receptor G6
BASP1 brain abundant, membrane attached signal protein 1
CLIC3 chloride intracellular channel 3
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
HIST1H2BG histone cluster 1, H2bg
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
KDM5D lysine (K)-specific demethylase 5D
MRPS16 mitochondrial ribosomal protein S16
PBX1 pre-B-cell leukemia homeobox 1
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
TFF1 trefoil factor 1
TSPAN8 tetraspanin 8
VNN1 vanin 1

decreased expression

Symbol Name
ADD3 adducin 3 (gamma)
AHR aryl hydrocarbon receptor
ARL4C ADP-ribosylation factor-like 4C
CNN3 calponin 3, acidic
CP ceruloplasmin (ferroxidase)
CSTA cystatin A (stefin A)
CXCL12 chemokine (C-X-C motif) ligand 12
DEGS1 delta(4)-desaturase, sphingolipid 1
EPB41L2 erythrocyte membrane protein band 4.1-like 2
FZD6 frizzled class receptor 6
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GPNMB glycoprotein (transmembrane) nmb
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HMGN3 high mobility group nucleosomal binding domain 3
HNRNPL heterogeneous nuclear ribonucleoprotein L
HPRT1 hypoxanthine phosphoribosyltransferase 1
IGFBP7 insulin-like growth factor binding protein 7
IGL immunoglobulin lambda locus
IGLL1 immunoglobulin lambda-like polypeptide 1
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MAN1A1 mannosidase, alpha, class 1A, member 1
MET MET proto-oncogene, receptor tyrosine kinase
MMP7 matrix metallopeptidase 7
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NOV nephroblastoma overexpressed
NRIP1 nuclear receptor interacting protein 1
PEG10 paternally expressed 10
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLAT plasminogen activator, tissue
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
S100A8 S100 calcium binding protein A8
SGCE sarcoglycan, epsilon
SMC1A structural maintenance of chromosomes 1A
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SYBU syntabulin (syntaxin-interacting)
WFDC2 WAP four-disulfide core domain 2