BRD-A20243730_Danazol_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

64 genes differentially expressed following the BRD-A20243730_Danazol_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADA adenosine deaminase
AREG amphiregulin
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CSK c-src tyrosine kinase
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNM1L dynamin 1-like
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GLRX glutaredoxin (thioltransferase)
IL32 interleukin 32
JCHAIN joining chain of multimeric IgA and IgM
KLF9 Kruppel-like factor 9
MAPK6 mitogen-activated protein kinase 6
MZB1 marginal zone B and B1 cell-specific protein
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PLIN2 perilipin 2
RHOBTB3 Rho-related BTB domain containing 3
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SCGB2A2 secretoglobin, family 2A, member 2
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SPDEF SAM pointed domain containing ETS transcription factor
SYBU syntabulin (syntaxin-interacting)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase

decreased expression

Symbol Name
ADGRE5 adhesion G protein-coupled receptor E5
AQP1 aquaporin 1 (Colton blood group)
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
B3GNT1
CCDC85B coiled-coil domain containing 85B
CCND1 cyclin D1
CCND2 cyclin D2
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEMIP cell migration inducing protein, hyaluronan binding
CX3CR1 chemokine (C-X3-C motif) receptor 1
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
EPS8 epidermal growth factor receptor pathway substrate 8
ESD esterase D
FLNA filamin A, alpha
GRWD1 glutamate-rich WD repeat containing 1
GTF3A general transcription factor IIIA
HEATR1 HEAT repeat containing 1
IGFBP3 insulin-like growth factor binding protein 3
KCTD12 potassium channel tetramerization domain containing 12
MYC v-myc avian myelocytomatosis viral oncogene homolog
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SRSF6 serine/arginine-rich splicing factor 6
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMEM97 transmembrane protein 97
TP53 tumor protein p53
TSPAN4 tetraspanin 4
TSPAN8 tetraspanin 8