BRD-A20131130_2,5-dideoxyadenosine_HCC15_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

114 genes differentially expressed following the BRD-A20131130_2,5-dideoxyadenosine_HCC15_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTG2 actin, gamma 2, smooth muscle, enteric
ADGRL2 adhesion G protein-coupled receptor L2
AHSP alpha hemoglobin stabilizing protein
ALB albumin
ARG2 arginase 2
ATF3 activating transcription factor 3
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BLNK B-cell linker
BTG2 BTG family, member 2
CA2 carbonic anhydrase II
CAST calpastatin
CCND2 cyclin D2
CD40 CD40 molecule, TNF receptor superfamily member 5
CHGB chromogranin B
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CNN1 calponin 1, basic, smooth muscle
COL4A5 collagen, type IV, alpha 5
COL4A6 collagen, type IV, alpha 6
CPE carboxypeptidase E
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL9 chemokine (C-X-C motif) ligand 9
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DPP4 dipeptidyl-peptidase 4
DSG2 desmoglein 2
DST dystonin
FABP6 fatty acid binding protein 6, ileal
FAM129A family with sequence similarity 129, member A
FILIP1L filamin A interacting protein 1-like
GAGE3 G antigen 3
GATA3 GATA binding protein 3
GNLY granulysin
HBD hemoglobin, delta
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IDO1 indoleamine 2,3-dioxygenase 1
IGHM immunoglobulin heavy constant mu
IGL immunoglobulin lambda locus
IPO13 importin 13
KLK2 kallikrein-related peptidase 2
KLK3 kallikrein-related peptidase 3
KRT23 keratin 23, type I
LGALS2 lectin, galactoside-binding, soluble, 2
LOC100505650 uncharacterized LOC100505650
MEIS2 Meis homeobox 2
MSMB microseminoprotein, beta-
NEFH neurofilament, heavy polypeptide
OLFM4 olfactomedin 4
PAGE4 P antigen family, member 4 (prostate associated)
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PCP4 Purkinje cell protein 4
PDE4B phosphodiesterase 4B, cAMP-specific
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLN phospholamban
PON3 paraoxonase 3
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PRKCH protein kinase C, eta
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RBM15B RNA binding motif protein 15B
RTN2 reticulon 2
S100A12 S100 calcium binding protein A12
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SCPEP1 serine carboxypeptidase 1
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SOCS2 suppressor of cytokine signaling 2
SULF1 sulfatase 1
TACSTD2 tumor-associated calcium signal transducer 2
TARP TCR gamma alternate reading frame protein
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TMEM158 transmembrane protein 158 (gene/pseudogene)
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3

decreased expression

Symbol Name
AGR2 anterior gradient 2
AK1 adenylate kinase 1
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
AP2B1 adaptor-related protein complex 2, beta 1 subunit
BAG2 BCL2-associated athanogene 2
BTN3A2 butyrophilin, subfamily 3, member A2
CHPT1 choline phosphotransferase 1
CXCL8 chemokine (C-X-C motif) ligand 8
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
EIF5A eukaryotic translation initiation factor 5A
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10
GANAB glucosidase, alpha; neutral AB
GPX3 glutathione peroxidase 3
GRWD1 glutamate-rich WD repeat containing 1
HOXC10 homeobox C10
HOXC6 homeobox C6
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFITM1 interferon induced transmembrane protein 1
IGFBP4 insulin-like growth factor binding protein 4
LAGE3 L antigen family, member 3
LTBP3 latent transforming growth factor beta binding protein 3
MARCKS myristoylated alanine-rich protein kinase C substrate
MET MET proto-oncogene, receptor tyrosine kinase
MSX1 msh homeobox 1
PSIP1 PC4 and SFRS1 interacting protein 1
RPA3 replication protein A3, 14kDa
S100A2 S100 calcium binding protein A2
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SRPX sushi-repeat containing protein, X-linked
TM9SF3 transmembrane 9 superfamily member 3
TNPO1 transportin 1
TSKU tsukushi, small leucine rich proteoglycan
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UGCG UDP-glucose ceramide glucosyltransferase
ZBTB38 zinc finger and BTB domain containing 38