BRD-A20126139_MEDRYSONE_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

68 genes differentially expressed following the BRD-A20126139_MEDRYSONE_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDOB aldolase B, fructose-bisphosphate
ANPEP alanyl (membrane) aminopeptidase
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast)
COL15A1 collagen, type XV, alpha 1
CSRP2 cysteine and glycine-rich protein 2
DPEP1 dipeptidase 1 (renal)
EPB41L3 erythrocyte membrane protein band 4.1-like 3
EZR ezrin
FOXO3 forkhead box O3
GLRX glutaredoxin (thioltransferase)
HBE1 hemoglobin, epsilon 1
HIST1H4C histone cluster 1, H4c
MXRA5 matrix-remodelling associated 5
NLRP2 NLR family, pyrin domain containing 2
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PLIN2 perilipin 2
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SFRP1 secreted frizzled-related protein 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
TCF4 transcription factor 4
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TUBB2A tubulin, beta 2A class IIa
VEGFA vascular endothelial growth factor A
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ADGRE5 adhesion G protein-coupled receptor E5
ALCAM activated leukocyte cell adhesion molecule
ANOS1 anosmin 1
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
CADM1 cell adhesion molecule 1
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1)
CDK4 cyclin-dependent kinase 4
CDK6 cyclin-dependent kinase 6
CORO1A coronin, actin binding protein, 1A
CSRP1 cysteine and glycine-rich protein 1
DHCR24 24-dehydrocholesterol reductase
EBNA1BP2 EBNA1 binding protein 2
ENC1 ectodermal-neural cortex 1 (with BTB domain)
ENOPH1 enolase-phosphatase 1
EPS8 epidermal growth factor receptor pathway substrate 8
FAM46A family with sequence similarity 46, member A
FLNA filamin A, alpha
GRSF1 G-rich RNA sequence binding factor 1
GSPT2 G1 to S phase transition 2
HNMT histamine N-methyltransferase
HSPH1 heat shock 105kDa/110kDa protein 1
IGFBP3 insulin-like growth factor binding protein 3
JAG1 jagged 1
LAMB3 laminin, beta 3
LMO3 LIM domain only 3 (rhombotin-like 2)
MMP7 matrix metallopeptidase 7
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MYC v-myc avian myelocytomatosis viral oncogene homolog
NPY1R neuropeptide Y receptor Y1
ODC1 ornithine decarboxylase 1
PUS7 pseudouridylate synthase 7 (putative)
RSL1D1 ribosomal L1 domain containing 1
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TM4SF1 transmembrane 4 L six family member 1
TSPAN8 tetraspanin 8
WASF3 WAS protein family, member 3
ZMYM2 zinc finger, MYM-type 2