BRD-A20126139_MEDRYSONE_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

122 genes differentially expressed following the BRD-A20126139_MEDRYSONE_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABLIM1 actin binding LIM protein 1
ADM adrenomedullin
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ALOX5AP arachidonate 5-lipoxygenase-activating protein
AQP3 aquaporin 3 (Gill blood group)
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
C1QB complement component 1, q subcomponent, B chain
CA1 carbonic anhydrase I
CA12 carbonic anhydrase XII
CD163 CD163 molecule
CLCA2 chloride channel accessory 2
COL3A1 collagen, type III, alpha 1
CP ceruloplasmin (ferroxidase)
DUSP2 dual specificity phosphatase 2
EGFR epidermal growth factor receptor
ELOVL5 ELOVL fatty acid elongase 5
ENO1 enolase 1, (alpha)
EPN2 epsin 2
EXPH5 exophilin 5
FASN fatty acid synthase
G6PD glucose-6-phosphate dehydrogenase
GFAP glial fibrillary acidic protein
GJA1 gap junction protein, alpha 1, 43kDa
GLUL glutamate-ammonia ligase
GPM6A glycoprotein M6A
HBB hemoglobin, beta
HILPDA hypoxia inducible lipid droplet-associated
HOPX HOP homeobox
IGL immunoglobulin lambda locus
IL4R interleukin 4 receptor
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
MAOA monoamine oxidase A
MBOAT7 membrane bound O-acyltransferase domain containing 7
NT5DC2 5'-nucleotidase domain containing 2
RGCC regulator of cell cycle
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SCGB1D2 secretoglobin, family 1D, member 2
SHROOM2 shroom family member 2
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SPRED2 sprouty-related, EVH1 domain containing 2
TCTA T-cell leukemia translocation altered
TSC22D3 TSC22 domain family, member 3
UGP2 UDP-glucose pyrophosphorylase 2
VSIG4 V-set and immunoglobulin domain containing 4

decreased expression

Symbol Name
ADGRG6 adhesion G protein-coupled receptor G6
ADIRF adipogenesis regulatory factor
ALB albumin
ALCAM activated leukocyte cell adhesion molecule
ALDOB aldolase B, fructose-bisphosphate
ASS1 argininosuccinate synthase 1
BBX bobby sox homolog (Drosophila)
BICC1 BicC family RNA binding protein 1
BUB3 BUB3 mitotic checkpoint protein
C7 complement component 7
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CFB complement factor B
CLDN1 claudin 1
COL14A1 collagen, type XIV, alpha 1
COL9A3 collagen, type IX, alpha 3
COLEC11 collectin sub-family member 11
CPVL carboxypeptidase, vitellogenic-like
CRISP3 cysteine-rich secretory protein 3
CRYBG3 beta-gamma crystallin domain containing 3
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DCN decorin
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DKK1 dickkopf WNT signaling pathway inhibitor 1
ELF1 E74-like factor 1 (ets domain transcription factor)
FABP1 fatty acid binding protein 1, liver
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM171A1 family with sequence similarity 171, member A1
G0S2 G0/G1 switch 2
GDF15 growth differentiation factor 15
GPC3 glypican 3
GPX2 glutathione peroxidase 2
GSTM3 glutathione S-transferase mu 3 (brain)
HOXC6 homeobox C6
IFI6 interferon, alpha-inducible protein 6
IGF1R insulin-like growth factor 1 receptor
IGFBP5 insulin-like growth factor binding protein 5
IL6ST interleukin 6 signal transducer
KNG1 kininogen 1
LCN2 lipocalin 2
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LXN latexin
LYZ lysozyme
MCUR1 mitochondrial calcium uniporter regulator 1
MYL9 myosin, light chain 9, regulatory
NID2 nidogen 2 (osteonidogen)
NPDC1 neural proliferation, differentiation and control, 1
NPY1R neuropeptide Y receptor Y1
PPIF peptidylprolyl isomerase F
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
PTMA prothymosin, alpha
PXDN peroxidasin
RBM25 RNA binding motif protein 25
REG1A regenerating islet-derived 1 alpha
RELN reelin
RPS11 ribosomal protein S11
RPS27L ribosomal protein S27-like
S100P S100 calcium binding protein P
SOX9 SRY (sex determining region Y)-box 9
SPINK1 serine peptidase inhibitor, Kazal type 1
SRRM2 serine/arginine repetitive matrix 2
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TFF1 trefoil factor 1
THBS1 thrombospondin 1
THBS2 thrombospondin 2
TM4SF4 transmembrane 4 L six family member 4
TSPAN8 tetraspanin 8
TSPYL5 TSPY-like 5
UGCG UDP-glucose ceramide glucosyltransferase