BRD-A20126139_-666_A549_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

159 genes differentially expressed following the BRD-A20126139_-666_A549_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADI1 acireductone dioxygenase 1
AHNAK2 AHNAK nucleoprotein 2
ALCAM activated leukocyte cell adhesion molecule
AQP3 aquaporin 3 (Gill blood group)
ASS1 argininosuccinate synthase 1
BAG1 BCL2-associated athanogene
BCL6 B-cell CLL/lymphoma 6
CALCA calcitonin-related polypeptide alpha
CD59 CD59 molecule, complement regulatory protein
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CFD complement factor D (adipsin)
COMP cartilage oligomeric matrix protein
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CSTA cystatin A (stefin A)
DDIT4 DNA-damage-inducible transcript 4
DHRS2 dehydrogenase/reductase (SDR family) member 2
DSP desmoplakin
DUSP1 dual specificity phosphatase 1
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
ENOPH1 enolase-phosphatase 1
F11R F11 receptor
F13A1 coagulation factor XIII, A1 polypeptide
FKBP5 FK506 binding protein 5
GADD45B growth arrest and DNA-damage-inducible, beta
GCH1 GTP cyclohydrolase 1
GLRX glutaredoxin (thioltransferase)
GLUL glutamate-ammonia ligase
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HMGN3 high mobility group nucleosomal binding domain 3
IGL immunoglobulin lambda locus
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
KLF2 Kruppel-like factor 2
KLF6 Kruppel-like factor 6
KLF9 Kruppel-like factor 9
KRT14 keratin 14, type I
KRT17 keratin 17, type I
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
LPL lipoprotein lipase
MAOA monoamine oxidase A
MTMR2 myotubularin related protein 2
MTSS1 metastasis suppressor 1
MYO1B myosin IB
NDRG1 N-myc downstream regulated 1
NEBL nebulette
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NUPR1 nuclear protein, transcriptional regulator, 1
PDLIM1 PDZ and LIM domain 1
PRKCD protein kinase C, delta
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTK2 protein tyrosine kinase 2
RGS2 regulator of G-protein signaling 2
RHOB ras homolog family member B
RNF167 ring finger protein 167
RPL37A ribosomal protein L37a
S100A14 S100 calcium binding protein A14
S100A2 S100 calcium binding protein A2
S100A8 S100 calcium binding protein A8
S100P S100 calcium binding protein P
SCG5 secretogranin V
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFN stratifin
SIK1 salt-inducible kinase 1
SIX2 SIX homeobox 2
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SQRDL sulfide quinone reductase-like (yeast)
STK26 serine/threonine protein kinase 26
STX1A syntaxin 1A (brain)
SYBU syntabulin (syntaxin-interacting)
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TMEM45A transmembrane protein 45A
TOB1 transducer of ERBB2, 1
TOX thymocyte selection-associated high mobility group box
TRAM2 translocation associated membrane protein 2
TRIM29 tripartite motif containing 29
TSC22D3 TSC22 domain family, member 3
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
VAMP8 vesicle-associated membrane protein 8
ZBTB16 zinc finger and BTB domain containing 16
ZFP36 ZFP36 ring finger protein
ZW10 zw10 kinetochore protein

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
AGR2 anterior gradient 2
ANXA1 annexin A1
ARL4C ADP-ribosylation factor-like 4C
CCL2 chemokine (C-C motif) ligand 2
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLDN10 claudin 10
CNN3 calponin 3, acidic
COL5A2 collagen, type V, alpha 2
COL6A1 collagen, type VI, alpha 1
COLEC12 collectin sub-family member 12
CRISP3 cysteine-rich secretory protein 3
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CST1 cystatin SN
CST4 cystatin S
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
CTSL cathepsin L
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
DST dystonin
EPB41L3 erythrocyte membrane protein band 4.1-like 3
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FKBP1A FK506 binding protein 1A, 12kDa
FOSL1 FOS-like antigen 1
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
HOXA5 homeobox A5
HSPA4 heat shock 70kDa protein 4
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IER3 immediate early response 3
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP3 insulin-like growth factor binding protein 3
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIAA0226L KIAA0226-like
LDB2 LIM domain binding 2
LGALS1 lectin, galactoside-binding, soluble, 1
LTF lactotransferrin
LXN latexin
MACF1 microtubule-actin crosslinking factor 1
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MEF2C myocyte enhancer factor 2C
MGP matrix Gla protein
MID1 midline 1
MMP7 matrix metallopeptidase 7
MPPED2 metallophosphoesterase domain containing 2
MTA1 metastasis associated 1
NPTX1 neuronal pentraxin I
OLFM4 olfactomedin 4
PCNA proliferating cell nuclear antigen
PDE4B phosphodiesterase 4B, cAMP-specific
PDLIM3 PDZ and LIM domain 3
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLAU plasminogen activator, urokinase
PLCL2 phospholipase C-like 2
PLK2 polo-like kinase 2
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
RANBP1 RAN binding protein 1
RAP1GAP RAP1 GTPase activating protein
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RUNX3 runt-related transcription factor 3
SCGB1D2 secretoglobin, family 1D, member 2
SFRP1 secreted frizzled-related protein 1
SIRPA signal-regulatory protein alpha
SMAD3 SMAD family member 3
SOX9 SRY (sex determining region Y)-box 9
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
TESC tescalcin
TMEM158 transmembrane protein 158 (gene/pseudogene)
TRIM2 tripartite motif containing 2
VTCN1 V-set domain containing T cell activation inhibitor 1
ZEB1 zinc finger E-box binding homeobox 1
ZNF586 zinc finger protein 586