BRD-A19918940_LOMATIN_HT29_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

105 genes differentially expressed following the BRD-A19918940_LOMATIN_HT29_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAM28 ADAM metallopeptidase domain 28
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
BAG1 BCL2-associated athanogene
CLU clusterin
COL4A5 collagen, type IV, alpha 5
CRTAP cartilage associated protein
CXCL10 chemokine (C-X-C motif) ligand 10
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DSG3 desmoglein 3
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
GCLC glutamate-cysteine ligase, catalytic subunit
GRIA2 glutamate receptor, ionotropic, AMPA 2
GSN gelsolin
GSTA4 glutathione S-transferase alpha 4
HBB hemoglobin, beta
IGHMBP2 immunoglobulin mu binding protein 2
ITGA6 integrin, alpha 6
KDM5D lysine (K)-specific demethylase 5D
KIAA0101 KIAA0101
KRT13 keratin 13, type I
KRT15 keratin 15, type I
KRT6A keratin 6A, type II
MBP myelin basic protein
MMP7 matrix metallopeptidase 7
NT5DC2 5'-nucleotidase domain containing 2
NUPR1 nuclear protein, transcriptional regulator, 1
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
PITX1 paired-like homeodomain 1
PRAME preferentially expressed antigen in melanoma
PRF1 perforin 1 (pore forming protein)
REEP1 receptor accessory protein 1
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A8 S100 calcium binding protein A8
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SPRR1A small proline-rich protein 1A
SPRR1B small proline-rich protein 1B
TACSTD2 tumor-associated calcium signal transducer 2
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGFBR3 transforming growth factor, beta receptor III
TM4SF1 transmembrane 4 L six family member 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10

decreased expression

Symbol Name
ACTN1 actinin, alpha 1
ADIRF adipogenesis regulatory factor
AEBP1 AE binding protein 1
ALDOB aldolase B, fructose-bisphosphate
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ANXA7 annexin A7
AREG amphiregulin
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
BGN biglycan
BID BH3 interacting domain death agonist
BRD4 bromodomain containing 4
CA2 carbonic anhydrase II
CLC Charcot-Leyden crystal galectin
CXCL12 chemokine (C-X-C motif) ligand 12
CYR61 cysteine-rich, angiogenic inducer, 61
DCN decorin
DKK3 dickkopf WNT signaling pathway inhibitor 3
DPYSL2 dihydropyrimidinase-like 2
GPX2 glutathione peroxidase 2
GREM1 gremlin 1, DAN family BMP antagonist
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HIST1H4C histone cluster 1, H4c
HSPA1A heat shock 70kDa protein 1A
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial
IFI44 interferon-induced protein 44
IFI6 interferon, alpha-inducible protein 6
INSR insulin receptor
LUC7L3 LUC7-like 3 (S. cerevisiae)
LY75 lymphocyte antigen 75
MAN1A1 mannosidase, alpha, class 1A, member 1
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MT1F metallothionein 1F
MT1X metallothionein 1X
MTDH metadherin
MXRA5 matrix-remodelling associated 5
NFIB nuclear factor I/B
NPTX2 neuronal pentraxin II
PCDH9 protocadherin 9
PDGFC platelet derived growth factor C
PECAM1 platelet/endothelial cell adhesion molecule 1
PRRC2C proline-rich coiled-coil 2C
PSD3 pleckstrin and Sec7 domain containing 3
PTMA prothymosin, alpha
RBM47 RNA binding motif protein 47
RDX radixin
RPS11 ribosomal protein S11
SFN stratifin
SKAP2 src kinase associated phosphoprotein 2
SMC1A structural maintenance of chromosomes 1A
SRSF6 serine/arginine-rich splicing factor 6
THBS2 thrombospondin 2
TNS1 tensin 1
TOB1 transducer of ERBB2, 1
TPBG trophoblast glycoprotein
TPR translocated promoter region, nuclear basket protein
TRIM2 tripartite motif containing 2
VCAN versican
XIST X inactive specific transcript (non-protein coding)
ZNF281 zinc finger protein 281