BRD-A19918940_LOMATIN_A549_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

70 genes differentially expressed following the BRD-A19918940_LOMATIN_A549_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALOX5 arachidonate 5-lipoxygenase
AQP9 aquaporin 9
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CCL20 chemokine (C-C motif) ligand 20
CD14 CD14 molecule
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCR4 chemokine (C-X-C motif) receptor 4
DPP4 dipeptidyl-peptidase 4
DPYD dihydropyrimidine dehydrogenase
FN1 fibronectin 1
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GRB7 growth factor receptor-bound protein 7
IFI44 interferon-induced protein 44
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
KCTD12 potassium channel tetramerization domain containing 12
LPAR6 lysophosphatidic acid receptor 6
MAN1A1 mannosidase, alpha, class 1A, member 1
MLPH melanophilin
MMP7 matrix metallopeptidase 7
MTSS1 metastasis suppressor 1
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
PRUNE2 prune homolog 2 (Drosophila)
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
SCUBE2 signal peptide, CUB domain, EGF-like 2
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SNN stannin
TCTA T-cell leukemia translocation altered
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TRIM13 tripartite motif containing 13
TSC22D1 TSC22 domain family, member 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGR2 anterior gradient 2
ALDOB aldolase B, fructose-bisphosphate
ANXA3 annexin A3
ANXA5 annexin A5
AXL AXL receptor tyrosine kinase
BACE2 beta-site APP-cleaving enzyme 2
CLTB clathrin, light chain B
CLU clusterin
CREB3L1 cAMP responsive element binding protein 3-like 1
CRIP1 cysteine-rich protein 1 (intestinal)
CTSG cathepsin G
DKK1 dickkopf WNT signaling pathway inhibitor 1
FGF13 fibroblast growth factor 13
FGFR1 fibroblast growth factor receptor 1
GLTP glycolipid transfer protein
GPX3 glutathione peroxidase 3
HOXC6 homeobox C6
HPRT1 hypoxanthine phosphoribosyltransferase 1
IFI27 interferon, alpha-inducible protein 27
LYRM4 LYR motif containing 4
MATN2 matrilin 2
MGP matrix Gla protein
MTA1 metastasis associated 1
PEBP1 phosphatidylethanolamine binding protein 1
POPDC3 popeye domain containing 3
PPAP2A phosphatidic acid phosphatase type 2A
RRAGD Ras-related GTP binding D
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SGCE sarcoglycan, epsilon
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SOX9 SRY (sex determining region Y)-box 9
SPRED2 sprouty-related, EVH1 domain containing 2
SPRY2 sprouty homolog 2 (Drosophila)
TFF3 trefoil factor 3 (intestinal)
THBS4 thrombospondin 4
TM9SF3 transmembrane 9 superfamily member 3
TSPAN8 tetraspanin 8