BRD-A19736161_ondansetron_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

33 genes differentially expressed following the BRD-A19736161_ondansetron_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALCAM activated leukocyte cell adhesion molecule
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
COL11A1 collagen, type XI, alpha 1
COL14A1 collagen, type XIV, alpha 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
FXYD3 FXYD domain containing ion transport regulator 3
GAB2 GRB2-associated binding protein 2
GPX2 glutathione peroxidase 2
IGFBP6 insulin-like growth factor binding protein 6
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
PLAGL1 pleiomorphic adenoma gene-like 1
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
TLE4 transducin-like enhancer of split 4
TPD52L1 tumor protein D52-like 1
TRIM22 tripartite motif containing 22

decreased expression

Symbol Name
ATM ATM serine/threonine kinase
CCL5 chemokine (C-C motif) ligand 5
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CXCL9 chemokine (C-X-C motif) ligand 9
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
LGALS1 lectin, galactoside-binding, soluble, 1
LIMCH1 LIM and calponin homology domains 1
MARCKS myristoylated alanine-rich protein kinase C substrate
MRPS16 mitochondrial ribosomal protein S16
NFIB nuclear factor I/B
NPTX2 neuronal pentraxin II
PRR7 proline rich 7 (synaptic)
RGS10 regulator of G-protein signaling 10
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SLC35F2 solute carrier family 35, member F2
TGOLN2 trans-golgi network protein 2
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
VWF von Willebrand factor