BRD-A19661776_-666_A549_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

62 genes differentially expressed following the BRD-A19661776_-666_A549_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AMIGO2 adhesion molecule with Ig-like domain 2
ASS1 argininosuccinate synthase 1
CALR calreticulin
CCL20 chemokine (C-C motif) ligand 20
CD3D CD3d molecule, delta (CD3-TCR complex)
CLDN4 claudin 4
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
DDAH1 dimethylarginine dimethylaminohydrolase 1
ENC1 ectodermal-neural cortex 1 (with BTB domain)
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
GPX3 glutathione peroxidase 3
GRB7 growth factor receptor-bound protein 7
GREM1 gremlin 1, DAN family BMP antagonist
IDI1 isopentenyl-diphosphate delta isomerase 1
IL13RA1 interleukin 13 receptor, alpha 1
IPO13 importin 13
MAN1A1 mannosidase, alpha, class 1A, member 1
MXRA7 matrix-remodelling associated 7
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTN pleiotrophin
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCG5 secretogranin V
SIRPA signal-regulatory protein alpha
TBC1D31 TBC1 domain family, member 31
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TGFA transforming growth factor, alpha
VEGFA vascular endothelial growth factor A
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ALCAM activated leukocyte cell adhesion molecule
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ANKRD10 ankyrin repeat domain 10
ATG3 autophagy related 3
BACE2 beta-site APP-cleaving enzyme 2
CD200 CD200 molecule
CDC42 cell division cycle 42
CDH19 cadherin 19, type 2
CRIP1 cysteine-rich protein 1 (intestinal)
CTTN cortactin
CXCL12 chemokine (C-X-C motif) ligand 12
EIF5 eukaryotic translation initiation factor 5
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM46A family with sequence similarity 46, member A
GAL galanin/GMAP prepropeptide
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFI27 interferon, alpha-inducible protein 27
IGFBP4 insulin-like growth factor binding protein 4
KIAA0125 KIAA0125
KRT10 keratin 10, type I
LY75 lymphocyte antigen 75
MFAP2 microfibrillar-associated protein 2
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
RAD23B RAD23 homolog B (S. cerevisiae)
RBP1 retinol binding protein 1, cellular
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SPRR1A small proline-rich protein 1A
TFF3 trefoil factor 3 (intestinal)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TYRP1 tyrosinase-related protein 1