BRD-A19633847_PERHEXILINE MALEATE_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

24 genes differentially expressed following the BRD-A19633847_PERHEXILINE MALEATE_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKR1C1 aldo-keto reductase family 1, member C1
BZW2 basic leucine zipper and W2 domains 2
CXCL2 chemokine (C-X-C motif) ligand 2
DUSP5 dual specificity phosphatase 5
GJA1 gap junction protein, alpha 1, 43kDa
HLA-B major histocompatibility complex, class I, B
MAP7 microtubule-associated protein 7
MTSS1 metastasis suppressor 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NPC1 Niemann-Pick disease, type C1
NUPR1 nuclear protein, transcriptional regulator, 1
OSBPL10 oxysterol binding protein-like 10
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
SQSTM1 sequestosome 1
TSPAN13 tetraspanin 13
WIPI1 WD repeat domain, phosphoinositide interacting 1

decreased expression

Symbol Name
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
FAM57A family with sequence similarity 57, member A
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
PFN2 profilin 2
TYRP1 tyrosinase-related protein 1
UBE2S ubiquitin-conjugating enzyme E2S