| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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188 genes differentially expressed following the BRD-A19500257_geldanamycin_MDAMB231_24_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| AQP3 | aquaporin 3 (Gill blood group) |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| B3GNT1 | |
| BAMBI | BMP and activin membrane-bound inhibitor |
| C1S | complement component 1, s subcomponent |
| CBLB | Cbl proto-oncogene B, E3 ubiquitin protein ligase |
| CCNG2 | cyclin G2 |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CLU | clusterin |
| CPM | carboxypeptidase M |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| CTSH | cathepsin H |
| DEFB1 | defensin, beta 1 |
| DHCR24 | 24-dehydrocholesterol reductase |
| DHCR7 | 7-dehydrocholesterol reductase |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DSTN | destrin (actin depolymerizing factor) |
| EFHD1 | EF-hand domain family, member D1 |
| EGF | epidermal growth factor |
| EGFL6 | EGF-like-domain, multiple 6 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 |
| FADS1 | fatty acid desaturase 1 |
| FAS | Fas cell surface death receptor |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 |
| FOSL2 | FOS-like antigen 2 |
| FTH1 | ferritin, heavy polypeptide 1 |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 |
| GLUL | glutamate-ammonia ligase |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HMOX1 | heme oxygenase 1 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA2 | heat shock 70kDa protein 2 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPA8 | heat shock 70kDa protein 8 |
| HSPB1 | heat shock 27kDa protein 1 |
| HSPE1 | heat shock 10kDa protein 1 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| HYOU1 | hypoxia up-regulated 1 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IL1R1 | interleukin 1 receptor, type I |
| IL1R2 | interleukin 1 receptor, type II |
| JAM3 | junctional adhesion molecule 3 |
| JMJD6 | jumonji domain containing 6 |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 |
| MAGED1 | melanoma antigen family D1 |
| MAGED2 | melanoma antigen family D2 |
| MAL | mal, T-cell differentiation protein |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 |
| MANF | mesencephalic astrocyte-derived neurotrophic factor |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| MSMO1 | methylsterol monooxygenase 1 |
| NEU1 | sialidase 1 (lysosomal sialidase) |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 |
| OBSL1 | obscurin-like 1 |
| OLFML3 | olfactomedin-like 3 |
| OSR2 | odd-skipped related transciption factor 2 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 |
| PLLP | plasmolipin |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) |
| QPRT | quinolinate phosphoribosyltransferase |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
| RGS2 | regulator of G-protein signaling 2 |
| RYBP | RING1 and YY1 binding protein |
| SAR1A | secretion associated, Ras related GTPase 1A |
| SC5D | sterol-C5-desaturase |
| SEC61G | Sec61 gamma subunit |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| SQLE | squalene epoxidase |
| SST | somatostatin |
| SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 |
| TBX3 | T-box 3 |
| TNNC1 | troponin C type 1 (slow) |
| TRAM1 | translocation associated membrane protein 1 |
| TSPAN13 | tetraspanin 13 |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) |
| ZNF331 | zinc finger protein 331 |
| Symbol | Name |
|---|---|
| ADRB2 | adrenoceptor beta 2, surface |
| ANXA3 | annexin A3 |
| AREG | amphiregulin |
| ARL4C | ADP-ribosylation factor-like 4C |
| ASPH | aspartate beta-hydroxylase |
| AXL | AXL receptor tyrosine kinase |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BRCA1 | breast cancer 1, early onset |
| C16ORF45 | chromosome 16 open reading frame 45 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
| CALML5 | calmodulin-like 5 |
| CAST | calpastatin |
| CCND1 | cyclin D1 |
| CCND2 | cyclin D2 |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CD44 | CD44 molecule (Indian blood group) |
| CDCP1 | CUB domain containing protein 1 |
| CEP170 | centrosomal protein 170kDa |
| CST1 | cystatin SN |
| CYBA | cytochrome b-245, alpha polypeptide |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 |
| DHFR | dihydrofolate reductase |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| DUSP4 | dual specificity phosphatase 4 |
| DUSP6 | dual specificity phosphatase 6 |
| EIF5A | eukaryotic translation initiation factor 5A |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) |
| EMP1 | epithelial membrane protein 1 |
| EPHB2 | EPH receptor B2 |
| EREG | epiregulin |
| ETV1 | ets variant 1 |
| ETV5 | ets variant 5 |
| F2R | coagulation factor II (thrombin) receptor |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
| FAM57A | family with sequence similarity 57, member A |
| FN1 | fibronectin 1 |
| FOSL1 | FOS-like antigen 1 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) |
| FXYD5 | FXYD domain containing ion transport regulator 5 |
| FZD7 | frizzled class receptor 7 |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| GPM6A | glycoprotein M6A |
| HHEX | hematopoietically expressed homeobox |
| HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
| IER3 | immediate early response 3 |
| IGFBP7 | insulin-like growth factor binding protein 7 |
| ITGA6 | integrin, alpha 6 |
| ITGB5 | integrin, beta 5 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 |
| LIG1 | ligase I, DNA, ATP-dependent |
| LOXL2 | lysyl oxidase-like 2 |
| LTF | lactotransferrin |
| MALL | mal, T-cell differentiation protein-like |
| MAP1B | microtubule-associated protein 1B |
| MCM2 | minichromosome maintenance complex component 2 |
| MCM3 | minichromosome maintenance complex component 3 |
| MCM4 | minichromosome maintenance complex component 4 |
| MCM5 | minichromosome maintenance complex component 5 |
| MCM6 | minichromosome maintenance complex component 6 |
| MCM7 | minichromosome maintenance complex component 7 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| MMP9 | matrix metallopeptidase 9 |
| MTHFD1 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| NELL2 | NEL-like 2 (chicken) |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PFKP | phosphofructokinase, platelet |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PLAU | plasminogen activator, urokinase |
| PLAUR | plasminogen activator, urokinase receptor |
| PNMA2 | paraneoplastic Ma antigen 2 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| PTHLH | parathyroid hormone-like hormone |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| RASA1 | RAS p21 protein activator (GTPase activating protein) 1 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 |
| SNX10 | sorting nexin 10 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like |
| TFDP1 | transcription factor Dp-1 |
| TFF3 | trefoil factor 3 (intestinal) |
| TGFB1 | transforming growth factor, beta 1 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TMEM47 | transmembrane protein 47 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 |
| WWTR1 | WW domain containing transcription regulator 1 |
