BRD-A19500257_geldanamycin_LNCAP_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

103 genes differentially expressed following the BRD-A19500257_geldanamycin_LNCAP_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARMCX3 armadillo repeat containing, X-linked 3
BAG3 BCL2-associated athanogene 3
CACYBP calcyclin binding protein
CALR calreticulin
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CLDN10 claudin 10
COL5A1 collagen, type V, alpha 1
CREB3L2 cAMP responsive element binding protein 3-like 2
CRELD2 cysteine-rich with EGF-like domains 2
CTSE cathepsin E
DDIT3 DNA-damage-inducible transcript 3
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
FOLR1 folate receptor 1 (adult)
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H1C histone cluster 1, H1c
HMOX1 heme oxygenase 1
HOOK2 hook microtubule-tethering protein 2
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPE1 heat shock 10kDa protein 1
HSPH1 heat shock 105kDa/110kDa protein 1
HYOU1 hypoxia up-regulated 1
IGHD immunoglobulin heavy constant delta
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGLV2-23 immunoglobulin lambda variable 2-23
JCHAIN joining chain of multimeric IgA and IgM
JMJD6 jumonji domain containing 6
JUN jun proto-oncogene
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
LTF lactotransferrin
MANF mesencephalic astrocyte-derived neurotrophic factor
MUC16 mucin 16, cell surface associated
MZB1 marginal zone B and B1 cell-specific protein
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PDIA4 protein disulfide isomerase family A, member 4
PLK2 polo-like kinase 2
PON3 paraoxonase 3
PPP1R15A protein phosphatase 1, regulatory subunit 15A
QPRT quinolinate phosphoribosyltransferase
RAD9A RAD9 homolog A (S. pombe)
RPL10 ribosomal protein L10
RPL27A ribosomal protein L27a
RPL38 ribosomal protein L38
SCGB2A1 secretoglobin, family 2A, member 1
SDF2L1 stromal cell-derived factor 2-like 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SFTPA2 surfactant protein A2
SFTPC surfactant protein C
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SPATS2L spermatogenesis associated, serine-rich 2-like
TNNC1 troponin C type 1 (slow)

decreased expression

Symbol Name
ACSL1 acyl-CoA synthetase long-chain family member 1
APOD apolipoprotein D
BCHE butyrylcholinesterase
BCL6 B-cell CLL/lymphoma 6
C1R complement component 1, r subcomponent
C9ORF16 chromosome 9 open reading frame 16
CA12 carbonic anhydrase XII
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CXADR coxsackie virus and adenovirus receptor
CXCL14 chemokine (C-X-C motif) ligand 14
DLD dihydrolipoamide dehydrogenase
EGR3 early growth response 3
GATA3 GATA binding protein 3
GBP2 guanylate binding protein 2, interferon-inducible
GPM6B glycoprotein M6B
GPX2 glutathione peroxidase 2
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
IGF1 insulin-like growth factor 1 (somatomedin C)
KYNU kynureninase
LMO3 LIM domain only 3 (rhombotin-like 2)
MCM3 minichromosome maintenance complex component 3
NAMPT nicotinamide phosphoribosyltransferase
NDN necdin, melanoma antigen (MAGE) family member
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NFIB nuclear factor I/B
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NPY1R neuropeptide Y receptor Y1
PCP4 Purkinje cell protein 4
PCSK1 proprotein convertase subtilisin/kexin type 1
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PROM1 prominin 1
PRPF4 pre-mRNA processing factor 4
PTGDS prostaglandin D2 synthase 21kDa (brain)
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
S100A8 S100 calcium binding protein A8
SOX11 SRY (sex determining region Y)-box 11
TFF3 trefoil factor 3 (intestinal)
TMSB15A thymosin beta 15a
TNC tenascin C
TOX3 TOX high mobility group box family member 3
TYRP1 tyrosinase-related protein 1