BRD-A19500257_geldanamycin_LNCAP_3_h_0.12_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

53 genes differentially expressed following the BRD-A19500257_geldanamycin_LNCAP_3_h_0.12_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AMIGO2 adhesion molecule with Ig-like domain 2
CACYBP calcyclin binding protein
CALR calreticulin
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CD24 CD24 molecule
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CKS2 CDC28 protein kinase regulatory subunit 2
CTSZ cathepsin Z
DENND2D DENN/MADD domain containing 2D
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA4L heat shock 70kDa protein 4-like
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPB1 heat shock 27kDa protein 1
HSPH1 heat shock 105kDa/110kDa protein 1
HYOU1 hypoxia up-regulated 1
JMJD6 jumonji domain containing 6
KRT23 keratin 23, type I
KRT7 keratin 7, type II
L1CAM L1 cell adhesion molecule
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
SDF2L1 stromal cell-derived factor 2-like 1
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
TGFBI transforming growth factor, beta-induced, 68kDa

decreased expression

Symbol Name
ACSL1 acyl-CoA synthetase long-chain family member 1
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
COCH cochlin
DEPTOR DEP domain containing MTOR-interacting protein
FABP4 fatty acid binding protein 4, adipocyte
FBLN2 fibulin 2
FGFR3 fibroblast growth factor receptor 3
FGG fibrinogen gamma chain
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
MTSS1 metastasis suppressor 1
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PPAP2B phosphatidic acid phosphatase type 2B
RGS5 regulator of G-protein signaling 5
SOX11 SRY (sex determining region Y)-box 11
SULF1 sulfatase 1
TMEM38B transmembrane protein 38B
XIST X inactive specific transcript (non-protein coding)