BRD-A19500257_geldanamycin_HME1_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

63 genes differentially expressed following the BRD-A19500257_geldanamycin_HME1_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
BAG3 BCL2-associated athanogene 3
CADM1 cell adhesion molecule 1
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CTSH cathepsin H
DDIT3 DNA-damage-inducible transcript 3
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
FOLR1 folate receptor 1 (adult)
H3F3B H3 histone, family 3B (H3.3B)
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPB1 heat shock 27kDa protein 1
HSPH1 heat shock 105kDa/110kDa protein 1
HYOU1 hypoxia up-regulated 1
IFI6 interferon, alpha-inducible protein 6
LIMCH1 LIM and calponin homology domains 1
MAGT1 magnesium transporter 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PMP22 peripheral myelin protein 22
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PTN pleiotrophin
RAD9A RAD9 homolog A (S. pombe)
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SCYL3 SCY1-like 3 (S. cerevisiae)
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SPP1 secreted phosphoprotein 1
TGFBI transforming growth factor, beta-induced, 68kDa
TMEM47 transmembrane protein 47
ZNF652 zinc finger protein 652

decreased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
ALDOB aldolase B, fructose-bisphosphate
ANGPTL4 angiopoietin-like 4
APOLD1 apolipoprotein L domain containing 1
AREG amphiregulin
CA1 carbonic anhydrase I
CD40 CD40 molecule, TNF receptor superfamily member 5
CD8A CD8a molecule
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CHGB chromogranin B
CRIP2 cysteine-rich protein 2
CXCL12 chemokine (C-X-C motif) ligand 12
FABP4 fatty acid binding protein 4, adipocyte
IER3 immediate early response 3
NCAM1 neural cell adhesion molecule 1
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PI3 peptidase inhibitor 3, skin-derived
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PRSS3 protease, serine, 3
PTGDS prostaglandin D2 synthase 21kDa (brain)
RGS2 regulator of G-protein signaling 2
SATB2 SATB homeobox 2
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SNAP25 synaptosomal-associated protein, 25kDa
TFF3 trefoil factor 3 (intestinal)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNS1 tensin 1
TSC22D3 TSC22 domain family, member 3
TSPAN12 tetraspanin 12