BRD-A19500257_geldanamycin_BT20_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

82 genes differentially expressed following the BRD-A19500257_geldanamycin_BT20_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
BAG3 BCL2-associated athanogene 3
CD24 CD24 molecule
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CLGN calmegin
CRELD2 cysteine-rich with EGF-like domains 2
CXCL5 chemokine (C-X-C motif) ligand 5
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
FOLR1 folate receptor 1 (adult)
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA1A heat shock 70kDa protein 1A
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPH1 heat shock 105kDa/110kDa protein 1
HYOU1 hypoxia up-regulated 1
IGKV1-5 immunoglobulin kappa variable 1-5
LMO4 LIM domain only 4
LPL lipoprotein lipase
MAGT1 magnesium transporter 1
MANF mesencephalic astrocyte-derived neurotrophic factor
ODC1 ornithine decarboxylase 1
PDE4DIP phosphodiesterase 4D interacting protein
PDIA6 protein disulfide isomerase family A, member 6
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
POLG2 polymerase (DNA directed), gamma 2, accessory subunit
PPIB peptidylprolyl isomerase B (cyclophilin B)
RAD9A RAD9 homolog A (S. pombe)
RGS1 regulator of G-protein signaling 1
RPL10 ribosomal protein L10
RPS11 ribosomal protein S11
RRAGD Ras-related GTP binding D
SDF2L1 stromal cell-derived factor 2-like 1
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
TARP TCR gamma alternate reading frame protein
TNS1 tensin 1
XBP1 X-box binding protein 1
ZDHHC6 zinc finger, DHHC-type containing 6
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ACTA2 actin, alpha 2, smooth muscle, aorta
ACTG2 actin, gamma 2, smooth muscle, enteric
CCND1 cyclin D1
CD93 CD93 molecule
CLU clusterin
CPB1 carboxypeptidase B1 (tissue)
CTGF connective tissue growth factor
CYR61 cysteine-rich, angiogenic inducer, 61
DKK3 dickkopf WNT signaling pathway inhibitor 3
DUSP1 dual specificity phosphatase 1
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FGFR3 fibroblast growth factor receptor 3
FRZB frizzled-related protein
GTPBP8 GTP-binding protein 8 (putative)
HES1 hes family bHLH transcription factor 1
IER3 immediate early response 3
IGF1 insulin-like growth factor 1 (somatomedin C)
IL7R interleukin 7 receptor
KRT15 keratin 15, type I
NEFL neurofilament, light polypeptide
NID1 nidogen 1
P3H2 prolyl 3-hydroxylase 2
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PID1 phosphotyrosine interaction domain containing 1
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
SEPT10 septin 10
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SNAI2 snail family zinc finger 2
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
THBS1 thrombospondin 1
TYMS thymidylate synthetase
ZMAT3 zinc finger, matrin-type 3