BRD-A19500257_geldanamycin_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

919 genes differentially expressed following the BRD-A19500257_geldanamycin_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AARS alanyl-tRNA synthetase
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABHD4 abhydrolase domain containing 4
ACOT13 acyl-CoA thioesterase 13
ACTA1 actin, alpha 1, skeletal muscle
ADA adenosine deaminase
ADCK3 aarF domain containing kinase 3
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADM adrenomedullin
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ANG angiogenin, ribonuclease, RNase A family, 5
APOD apolipoprotein D
AQP3 aquaporin 3 (Gill blood group)
AQP4 aquaporin 4
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ARMCX3 armadillo repeat containing, X-linked 3
ASNS asparagine synthetase (glutamine-hydrolyzing)
ASRGL1 asparaginase like 1
ASS1 argininosuccinate synthase 1
ATF3 activating transcription factor 3
ATF4 activating transcription factor 4
ATHL1 ATH1, acid trehalase-like 1 (yeast)
ATMIN ATM interactor
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP2A3 ATPase, Ca++ transporting, ubiquitous
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
BAG2 BCL2-associated athanogene 2
BAG3 BCL2-associated athanogene 3
BASP1 brain abundant, membrane attached signal protein 1
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BCL6 B-cell CLL/lymphoma 6
BEX4 brain expressed, X-linked 4
BLNK B-cell linker
BSG basigin (Ok blood group)
C14ORF132 chromosome 14 open reading frame 132
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
C1S complement component 1, s subcomponent
C3 complement component 3
C4BPA complement component 4 binding protein, alpha
C9ORF91 chromosome 9 open reading frame 91
CA1 carbonic anhydrase I
CA2 carbonic anhydrase II
CACYBP calcyclin binding protein
CADPS2 Ca++-dependent secretion activator 2
CALR calreticulin
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CANX calnexin
CAPG capping protein (actin filament), gelsolin-like
CAPN6 calpain 6
CARS cysteinyl-tRNA synthetase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CBS cystathionine-beta-synthase
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCNE1 cyclin E1
CD14 CD14 molecule
CD163 CD163 molecule
CD52 CD52 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDK19 cyclin-dependent kinase 19
CDK2AP2 cyclin-dependent kinase 2 associated protein 2
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CECR1 cat eye syndrome chromosome region, candidate 1
CELF2 CUGBP, Elav-like family member 2
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHI3L2 chitinase 3-like 2
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CKB creatine kinase, brain
CLDN10 claudin 10
CLDN3 claudin 3
CLEC2B C-type lectin domain family 2, member B
CLIP1 CAP-GLY domain containing linker protein 1
CLN5 ceroid-lipofuscinosis, neuronal 5
CLU clusterin
COBL cordon-bleu WH2 repeat protein
COBLL1 cordon-bleu WH2 repeat protein-like 1
COL3A1 collagen, type III, alpha 1
COL4A5 collagen, type IV, alpha 5
COL5A2 collagen, type V, alpha 2
COPA coatomer protein complex, subunit alpha
CORO1A coronin, actin binding protein, 1A
CPD carboxypeptidase D
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CRABP2 cellular retinoic acid binding protein 2
CREB3L2 cAMP responsive element binding protein 3-like 2
CREG1 cellular repressor of E1A-stimulated genes 1
CRELD2 cysteine-rich with EGF-like domains 2
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CRYAB crystallin, alpha B
CRYZ crystallin, zeta (quinone reductase)
CSRP1 cysteine and glycine-rich protein 1
CST3 cystatin C
CSTA cystatin A (stefin A)
CTSB cathepsin B
CTSH cathepsin H
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL8 chemokine (C-X-C motif) ligand 8
CYB561 cytochrome b561
CYB5R1 cytochrome b5 reductase 1
CYBA cytochrome b-245, alpha polypeptide
CYBB cytochrome b-245, beta polypeptide
CYFIP2 cytoplasmic FMR1 interacting protein 2
CYTIP cytohesin 1 interacting protein
DCN decorin
DDIT3 DNA-damage-inducible transcript 3
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DEFB1 defensin, beta 1
DERL2 derlin 2
DES desmin
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLK1 delta-like 1 homolog (Drosophila)
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DPYSL2 dihydropyrimidinase-like 2
DST dystonin
EAF2 ELL associated factor 2
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EFHD1 EF-hand domain family, member D1
EGFR epidermal growth factor receptor
EIF1 eukaryotic translation initiation factor 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EIF5A eukaryotic translation initiation factor 5A
ELANE elastase, neutrophil expressed
ELOVL5 ELOVL fatty acid elongase 5
EMX2 empty spiracles homeobox 2
ENC1 ectodermal-neural cortex 1 (with BTB domain)
ENO1 enolase 1, (alpha)
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPHB2 EPH receptor B2
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ESR1 estrogen receptor 1
ETNPPL ethanolamine-phosphate phospho-lyase
EVI2A ecotropic viral integration site 2A
F2RL1 coagulation factor II (thrombin) receptor-like 1
F3 coagulation factor III (thromboplastin, tissue factor)
FAM129A family with sequence similarity 129, member A
FAM46A family with sequence similarity 46, member A
FASN fatty acid synthase
FBLN1 fibulin 1
FBN2 fibrillin 2
FBP1 fructose-1,6-bisphosphatase 1
FBXO11 F-box protein 11
FCGBP Fc fragment of IgG binding protein
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FGB fibrinogen beta chain
FGFR2 fibroblast growth factor receptor 2
FGG fibrinogen gamma chain
FICD FIC domain containing
FKBP11 FK506 binding protein 11, 19 kDa
FLOT1 flotillin 1
FN1 fibronectin 1
FOLR1 folate receptor 1 (adult)
FTH1 ferritin, heavy polypeptide 1
FXYD3 FXYD domain containing ion transport regulator 3
G6PD glucose-6-phosphate dehydrogenase
GABARAPL1 GABA(A) receptor-associated protein like 1
GADD45B growth arrest and DNA-damage-inducible, beta
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7
GAS6 growth arrest-specific 6
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GFPT1 glutamine--fructose-6-phosphate transaminase 1
GJA1 gap junction protein, alpha 1, 43kDa
GLRX glutaredoxin (thioltransferase)
GLTSCR2 glioma tumor suppressor candidate region gene 2
GLUL glutamate-ammonia ligase
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GOLM1 golgi membrane protein 1
GORASP2 golgi reassembly stacking protein 2, 55kDa
GPER1 G protein-coupled estrogen receptor 1
GPRASP1 G protein-coupled receptor associated sorting protein 1
GPRC5A G protein-coupled receptor, class C, group 5, member A
GRB7 growth factor receptor-bound protein 7
GRIA2 glutamate receptor, ionotropic, AMPA 2
GSTA1 glutathione S-transferase alpha 1
GSTZ1 glutathione S-transferase zeta 1
GUSBP11 glucuronidase, beta pseudogene 11
GUSBP3 glucuronidase, beta pseudogene 3
HBB hemoglobin, beta
HCLS1 hematopoietic cell-specific Lyn substrate 1
HEBP1 heme binding protein 1
HEBP2 heme binding protein 2
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H2BG histone cluster 1, H2bg
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HOPX HOP homeobox
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA13 heat shock protein 70kDa family, member 13
HSPA1A heat shock 70kDa protein 1A
HSPA2 heat shock 70kDa protein 2
HSPA4L heat shock 70kDa protein 4-like
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPB1 heat shock 27kDa protein 1
HSPB8 heat shock 22kDa protein 8
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPE1 heat shock 10kDa protein 1
HSPH1 heat shock 105kDa/110kDa protein 1
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
HYOU1 hypoxia up-regulated 1
ICAM1 intercellular adhesion molecule 1
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IER5 immediate early response 5
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGHM immunoglobulin heavy constant mu
IGHMBP2 immunoglobulin mu binding protein 2
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
IGLJ3 immunoglobulin lambda joining 3
IGLV2-23 immunoglobulin lambda variable 2-23
IL1R2 interleukin 1 receptor, type II
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
INHBE inhibin, beta E
IQCK IQ motif containing K
IQGAP1 IQ motif containing GTPase activating protein 1
IRF9 interferon regulatory factor 9
IRS2 insulin receptor substrate 2
ISLR immunoglobulin superfamily containing leucine-rich repeat
ITM2A integral membrane protein 2A
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JCHAIN joining chain of multimeric IgA and IgM
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCTD12 potassium channel tetramerization domain containing 12
KCTD5 potassium channel tetramerization domain containing 5
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KDM5D lysine (K)-specific demethylase 5D
KIAA1598
KLHL41 kelch-like family member 41
KLK10 kallikrein-related peptidase 10
KLK11 kallikrein-related peptidase 11
KLK5 kallikrein-related peptidase 5
KLK6 kallikrein-related peptidase 6
KLK7 kallikrein-related peptidase 7
KLK8 kallikrein-related peptidase 8
KRT13 keratin 13, type I
KRT19 keratin 19, type I
KRT23 keratin 23, type I
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
KRT7 keratin 7, type II
LAMP3 lysosomal-associated membrane protein 3
LAMP5 lysosomal-associated membrane protein family, member 5
LAPTM4B lysosomal protein transmembrane 4 beta
LCN2 lipocalin 2
LDB3 LIM domain binding 3
LGALS2 lectin, galactoside-binding, soluble, 2
LIMCH1 LIM and calponin homology domains 1
LITAF lipopolysaccharide-induced TNF factor
LMO3 LIM domain only 3 (rhombotin-like 2)
LMO4 LIM domain only 4
LOC100505650 uncharacterized LOC100505650
LPAR1 lysophosphatidic acid receptor 1
LTF lactotransferrin
LXN latexin
LY96 lymphocyte antigen 96
LYN LYN proto-oncogene, Src family tyrosine kinase
LYZ lysozyme
MAGT1 magnesium transporter 1
MALL mal, T-cell differentiation protein-like
MAN2A1 mannosidase, alpha, class 2A, member 1
MANF mesencephalic astrocyte-derived neurotrophic factor
MAOA monoamine oxidase A
MAOB monoamine oxidase B
MAP1B microtubule-associated protein 1B
MAP2K1 mitogen-activated protein kinase kinase 1
MAP7 microtubule-associated protein 7
MAPK13 mitogen-activated protein kinase 13
MATN2 matrilin 2
MB myoglobin
MBOAT7 membrane bound O-acyltransferase domain containing 7
MCTP1 multiple C2 domains, transmembrane 1
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial
MEF2C myocyte enhancer factor 2C
MERTK MER proto-oncogene, tyrosine kinase
MFSD10 major facilitator superfamily domain containing 10
MICB MHC class I polypeptide-related sequence B
MIR22HG MIR22 host gene
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MLPH melanophilin
MMP1 matrix metallopeptidase 1
MMP9 matrix metallopeptidase 9
MOCOS molybdenum cofactor sulfurase
MORC4 MORC family CW-type zinc finger 4
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MSLN mesothelin
MSMB microseminoprotein, beta-
MSMO1 methylsterol monooxygenase 1
MSRB1 methionine sulfoxide reductase B1
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1M metallothionein 1M
MTMR4 myotubularin related protein 4
MTUS1 microtubule associated tumor suppressor 1
MUC16 mucin 16, cell surface associated
MUC4 mucin 4, cell surface associated
MUC5B mucin 5B, oligomeric mucus/gel-forming
MVP major vault protein
MYBPC1 myosin binding protein C, slow type
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYDGF myeloid-derived growth factor
MYO10 myosin X
MZB1 marginal zone B and B1 cell-specific protein
N4BP2L2 NEDD4 binding protein 2-like 2
NAGK N-acetylglucosamine kinase
NAMPT nicotinamide phosphoribosyltransferase
NANS N-acetylneuraminic acid synthase
NDRG1 N-myc downstream regulated 1
NEB nebulin
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NEU1 sialidase 1 (lysosomal sialidase)
NKX3-1 NK3 homeobox 1
NNMT nicotinamide N-methyltransferase
NQO1 NAD(P)H dehydrogenase, quinone 1
NRCAM neuronal cell adhesion molecule
NRGN neurogranin (protein kinase C substrate, RC3)
NT5DC2 5'-nucleotidase domain containing 2
NUCB2 nucleobindin 2
NUPR1 nuclear protein, transcriptional regulator, 1
NXN nucleoredoxin
OAT ornithine aminotransferase
ODC1 ornithine decarboxylase 1
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
P4HB prolyl 4-hydroxylase, beta polypeptide
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PCP4 Purkinje cell protein 4
PDE4B phosphodiesterase 4B, cAMP-specific
PDIA3 protein disulfide isomerase family A, member 3
PDIA4 protein disulfide isomerase family A, member 4
PDIA6 protein disulfide isomerase family A, member 6
PEG3 paternally expressed 3
PENK proenkephalin
PERP PERP, TP53 apoptosis effector
PHACTR2 phosphatase and actin regulator 2
PI3 peptidase inhibitor 3, skin-derived
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PIR pirin (iron-binding nuclear protein)
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLAC8 placenta-specific 8
PLD3 phospholipase D family, member 3
PLTP phospholipid transfer protein
PMP22 peripheral myelin protein 22
PNKP polynucleotide kinase 3'-phosphatase
PON3 paraoxonase 3
POU2AF1 POU class 2 associating factor 1
PPAP2B phosphatidic acid phosphatase type 2B
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PPIB peptidylprolyl isomerase B (cyclophilin B)
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRAME preferentially expressed antigen in melanoma
PRDX2 peroxiredoxin 2
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
PRSS8 protease, serine, 8
PRTN3 proteinase 3
PSAP prosaposin
PSAT1 phosphoserine aminotransferase 1
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGES prostaglandin E synthase
PTP4A1 protein tyrosine phosphatase type IVA, member 1
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PYCR1 pyrroline-5-carboxylate reductase 1
QDPR quinoid dihydropteridine reductase
QKI QKI, KH domain containing, RNA binding
QPRT quinolinate phosphoribosyltransferase
RAB15 RAB15, member RAS oncogene family
RAD9A RAD9 homolog A (S. pombe)
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RGCC regulator of cell cycle
RGS1 regulator of G-protein signaling 1
RGS10 regulator of G-protein signaling 10
RGS2 regulator of G-protein signaling 2
RHOB ras homolog family member B
RHOQ ras homolog family member Q
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RNASE4 ribonuclease, RNase A family, 4
RNASE6 ribonuclease, RNase A family, k6
RNASET2 ribonuclease T2
RPL38 ribosomal protein L38
RPS11 ribosomal protein S11
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RRBP1 ribosome binding protein 1
RTN1 reticulon 1
S100A14 S100 calcium binding protein A14
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
S100P S100 calcium binding protein P
SAT1 spermidine/spermine N1-acetyltransferase 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SCGB2A2 secretoglobin, family 2A, member 2
SCN3A sodium channel, voltage gated, type III alpha subunit
SCUBE2 signal peptide, CUB domain, EGF-like 2
SDF2L1 stromal cell-derived factor 2-like 1
SEC24D SEC24 family member D
SEC61B Sec61 beta subunit
SEC63 SEC63 homolog (S. cerevisiae)
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SELENBP1 selenium binding protein 1
SEPW1 selenoprotein W, 1
SERP1 stress-associated endoplasmic reticulum protein 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SFN stratifin
SFRP4 secreted frizzled-related protein 4
SFTPB surfactant protein B
SFTPC surfactant protein C
SFTPD surfactant protein D
SGK1 serum/glucocorticoid regulated kinase 1
SH3YL1 SH3 and SYLF domain containing 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SIK1 salt-inducible kinase 1
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1
SLC35B1 solute carrier family 35, member B1
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SLPI secretory leukocyte peptidase inhibitor
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOD2 superoxide dismutase 2, mitochondrial
SORBS2 sorbin and SH3 domain containing 2
SOX9 SRY (sex determining region Y)-box 9
SPARCL1 SPARC-like 1 (hevin)
SPON1 spondin 1, extracellular matrix protein
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
SPRED2 sprouty-related, EVH1 domain containing 2
SRGN serglycin
SRPR signal recognition particle receptor (docking protein)
SRPRB signal recognition particle receptor, B subunit
SSR4 signal sequence receptor, delta
SST somatostatin
ST18 suppression of tumorigenicity 18, zinc finger
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
STC2 stanniocalcin 2
STK17B serine/threonine kinase 17b
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
SV2C synaptic vesicle glycoprotein 2C
SYK spleen tyrosine kinase
TACC2 transforming, acidic coiled-coil containing protein 2
TALDO1 transaldolase 1
TDP2 tyrosyl-DNA phosphodiesterase 2
TFF3 trefoil factor 3 (intestinal)
TFPI2 tissue factor pathway inhibitor 2
THBS2 thrombospondin 2
TMED10 transmembrane emp24-like trafficking protein 10 (yeast)
TMED2 transmembrane emp24 domain trafficking protein 2
TMEM41B transmembrane protein 41B
TMEM45A transmembrane protein 45A
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNNC1 troponin C type 1 (slow)
TNNT1 troponin T type 1 (skeletal, slow)
TPD52 tumor protein D52
TPST2 tyrosylprotein sulfotransferase 2
TRA2A transformer 2 alpha homolog (Drosophila)
TRAM1 translocation associated membrane protein 1
TRIB3 tribbles pseudokinase 3
TRIM29 tripartite motif containing 29
TSPAN13 tetraspanin 13
TSPAN7 tetraspanin 7
TSPYL5 TSPY-like 5
TTC3 tetratricopeptide repeat domain 3
TTN titin
TXN thioredoxin
TXNDC15 thioredoxin domain containing 15
TXNDC9 thioredoxin domain containing 9
TYMP thymidine phosphorylase
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
UBE2J1 ubiquitin-conjugating enzyme E2, J1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UGDH UDP-glucose 6-dehydrogenase
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17
UNC13B unc-13 homolog B (C. elegans)
USP3 ubiquitin specific peptidase 3
VCP valosin containing protein
VSIG4 V-set and immunoglobulin domain containing 4
VWF von Willebrand factor
WARS tryptophanyl-tRNA synthetase
WDTC1 WD and tetratricopeptide repeats 1
WFS1 Wolfram syndrome 1 (wolframin)
WIF1 WNT inhibitory factor 1
XBP1 X-box binding protein 1
XIST X inactive specific transcript (non-protein coding)
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZNF165 zinc finger protein 165
ZNF331 zinc finger protein 331
ZNF451 zinc finger protein 451
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ACACB acetyl-CoA carboxylase beta
ACP5 acid phosphatase 5, tartrate resistant
ACTN4 actinin, alpha 4
ADD3 adducin 3 (gamma)
ADI1 acireductone dioxygenase 1
ADIPOQ adiponectin, C1Q and collagen domain containing
ADIRF adipogenesis regulatory factor
AGTR1 angiotensin II receptor, type 1
AKAP12 A kinase (PRKA) anchor protein 12
AKAP8 A kinase (PRKA) anchor protein 8
ALB albumin
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALDOB aldolase B, fructose-bisphosphate
ALOX5 arachidonate 5-lipoxygenase
AMIGO2 adhesion molecule with Ig-like domain 2
ANPEP alanyl (membrane) aminopeptidase
ANXA10 annexin A10
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
AREG amphiregulin
ARG1 arginase 1
ARL4C ADP-ribosylation factor-like 4C
ASPN asporin
ATF5 activating transcription factor 5
ATG3 autophagy related 3
ATP10A ATPase, class V, type 10A
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
AURKA aurora kinase A
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BEX1 brain expressed, X-linked 1
BHLHE41 basic helix-loop-helix family, member e41
BMP2 bone morphogenetic protein 2
BST2 bone marrow stromal cell antigen 2
BTG1 B-cell translocation gene 1, anti-proliferative
CA12 carbonic anhydrase XII
CAB39 calcium binding protein 39
CADM1 cell adhesion molecule 1
CARHSP1 calcium regulated heat stable protein 1, 24kDa
CAST calpastatin
CAT catalase
CCL5 chemokine (C-C motif) ligand 5
CCND1 cyclin D1
CCND2 cyclin D2
CCNE2 cyclin E2
CCNF cyclin F
CD200 CD200 molecule
CD24 CD24 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD47 CD47 molecule
CD58 CD58 molecule
CD59 CD59 molecule, complement regulatory protein
CD8A CD8a molecule
CD9 CD9 molecule
CD96 CD96 molecule
CDC25B cell division cycle 25B
CDCA4 cell division cycle associated 4
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDV3 CDV3 homolog (mouse)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEMIP cell migration inducing protein, hyaluronan binding
CENPU centromere protein U
CETN3 centrin, EF-hand protein, 3
CHRDL1 chordin-like 1
COASY CoA synthase
COL10A1 collagen, type X, alpha 1
COL6A3 collagen, type VI, alpha 3
COPS7A COP9 signalosome subunit 7A
CPB1 carboxypeptidase B1 (tissue)
CPE carboxypeptidase E
CREB1 cAMP responsive element binding protein 1
CRISP3 cysteine-rich secretory protein 3
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CSRP2 cysteine and glycine-rich protein 2
CST7 cystatin F (leukocystatin)
CTPS1 CTP synthase 1
CTSW cathepsin W
CXADR coxsackie virus and adenovirus receptor
CXCL14 chemokine (C-X-C motif) ligand 14
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
CYR61 cysteine-rich, angiogenic inducer, 61
CYTL1 cytokine-like 1
DCBLD2 discoidin, CUB and LCCL domain containing 2
DDB2 damage-specific DNA binding protein 2, 48kDa
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DEPTOR DEP domain containing MTOR-interacting protein
DHRS3 dehydrogenase/reductase (SDR family) member 3
DKK3 dickkopf WNT signaling pathway inhibitor 3
DLC1 DLC1 Rho GTPase activating protein
DNM1L dynamin 1-like
DPYSL3 dihydropyrimidinase-like 3
DUOX2 dual oxidase 2
DUSP6 dual specificity phosphatase 6
EDNRB endothelin receptor type B
EGR3 early growth response 3
EHD3 EH-domain containing 3
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
EMG1 EMG1 N1-specific pseudouridine methyltransferase
EMP2 epithelial membrane protein 2
EPS8 epidermal growth factor receptor pathway substrate 8
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
EXOSC4 exosome component 4
F2R coagulation factor II (thrombin) receptor
F5 coagulation factor V (proaccelerin, labile factor)
FABP1 fatty acid binding protein 1, liver
FABP4 fatty acid binding protein 4, adipocyte
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM57A family with sequence similarity 57, member A
FAP fibroblast activation protein, alpha
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
FBXO21 F-box protein 21
FCMR Fc fragment of IgM receptor
FHL1 four and a half LIM domains 1
FILIP1L filamin A interacting protein 1-like
FNBP1L formin binding protein 1-like
FNDC3B fibronectin type III domain containing 3B
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FRZB frizzled-related protein
FST follistatin
FUBP1 far upstream element (FUSE) binding protein 1
FZD6 frizzled class receptor 6
FZD7 frizzled class receptor 7
GAS1 growth arrest-specific 1
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GMPS guanine monphosphate synthase
GOLGA8A golgin A8 family, member A
GPX3 glutathione peroxidase 3
GRAMD1C GRAM domain containing 1C
GRB14 growth factor receptor-bound protein 14
GREM1 gremlin 1, DAN family BMP antagonist
GSN gelsolin
GSTM3 glutathione S-transferase mu 3 (brain)
H1F0 H1 histone family, member 0
HDAC9 histone deacetylase 9
HES1 hes family bHLH transcription factor 1
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HIST1H2AC histone cluster 1, H2ac
HIST1H4C histone cluster 1, H4c
HLA-DMA major histocompatibility complex, class II, DM alpha
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HMGA2 high mobility group AT-hook 2
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
HN1 hematological and neurological expressed 1
HOXA10 homeobox A10
HOXA5 homeobox A5
HOXB2 homeobox B2
HOXB7 homeobox B7
HOXC6 homeobox C6
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IER3 immediate early response 3
IFI27 interferon, alpha-inducible protein 27
IFI44 interferon-induced protein 44
IFI44L interferon-induced protein 44-like
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM1 interferon induced transmembrane protein 1
IFRD2 interferon-related developmental regulator 2
IGF1R insulin-like growth factor 1 receptor
IGLL1 immunoglobulin lambda-like polypeptide 1
IGSF3 immunoglobulin superfamily, member 3
IL13RA2 interleukin 13 receptor, alpha 2
IL1B interleukin 1, beta
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
IRAK1 interleukin-1 receptor-associated kinase 1
IRS1 insulin receptor substrate 1
ISG15 ISG15 ubiquitin-like modifier
ITGAV integrin, alpha V
JADE2 jade family PHD finger 2
KIF1BP KIF1 binding protein
KIF20A kinesin family member 20A
KLF6 Kruppel-like factor 6
KNG1 kininogen 1
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
KRT10 keratin 10, type I
KRT14 keratin 14, type I
KRT17 keratin 17, type I
KRT20 keratin 20, type I
L1CAM L1 cell adhesion molecule
LAMB1 laminin, beta 1
LEPR leptin receptor
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LPL lipoprotein lipase
LRRN3 leucine rich repeat neuronal 3
LUC7L3 LUC7-like 3 (S. cerevisiae)
LYPD1 LY6/PLAUR domain containing 1
MAB21L2 mab-21-like 2 (C. elegans)
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MALT1 MALT1 paracaspase
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like
MBNL1 muscleblind-like splicing regulator 1
MCAM melanoma cell adhesion molecule
MCM3 minichromosome maintenance complex component 3
MCM7 minichromosome maintenance complex component 7
MEIS2 Meis homeobox 2
MET MET proto-oncogene, receptor tyrosine kinase
METTL7A methyltransferase like 7A
MFAP2 microfibrillar-associated protein 2
MGLL monoglyceride lipase
MIA melanoma inhibitory activity
MMP7 matrix metallopeptidase 7
MOK MOK protein kinase
MRPL12 mitochondrial ribosomal protein L12
MSH6 mutS homolog 6
MX2 MX dynamin-like GTPase 2
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYH10 myosin, heavy chain 10, non-muscle
NAV2 neuron navigator 2
NDN necdin, melanoma antigen (MAGE) family member
NFIB nuclear factor I/B
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NID1 nidogen 1
NKG7 natural killer cell granule protein 7
NKTR natural killer cell triggering receptor
NMU neuromedin U
NOV nephroblastoma overexpressed
NPTX2 neuronal pentraxin II
NPY1R neuropeptide Y receptor Y1
NR2F2 nuclear receptor subfamily 2, group F, member 2
NREP neuronal regeneration related protein
NRIP1 nuclear receptor interacting protein 1
NRN1 neuritin 1
NTM neurotrimin
NTS neurotensin
NUAK1 NUAK family, SNF1-like kinase, 1
OGDHL oxoglutarate dehydrogenase-like
ORC1 origin recognition complex, subunit 1
OSBPL10 oxysterol binding protein-like 10
OXA1L oxidase (cytochrome c) assembly 1-like
PARP2 poly (ADP-ribose) polymerase 2
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PCNA proliferating cell nuclear antigen
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDZRN3 PDZ domain containing ring finger 3
PEG10 paternally expressed 10
PER2 period circadian clock 2
PGAM1 phosphoglycerate mutase 1 (brain)
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLAGL1 pleiomorphic adenoma gene-like 1
PLAT plasminogen activator, tissue
PLCB4 phospholipase C, beta 4
PLIN1 perilipin 1
PLK1 polo-like kinase 1
PLN phospholamban
PNMA1 paraneoplastic Ma antigen 1
PNMA2 paraneoplastic Ma antigen 2
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
POSTN periostin, osteoblast specific factor
PPARG peroxisome proliferator-activated receptor gamma
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha
PRKCI protein kinase C, iota
PROM1 prominin 1
PRSS23 protease, serine, 23
PRSS3 protease, serine, 3
PSRC1 proline/serine-rich coiled-coil 1
PTCH1 patched 1
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTMA prothymosin, alpha
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
PUF60 poly-U binding splicing factor 60KDa
QPCT glutaminyl-peptide cyclotransferase
RAP2A RAP2A, member of RAS oncogene family
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RBP4 retinol binding protein 4, plasma
RELN reelin
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RGS5 regulator of G-protein signaling 5
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
RNF43 ring finger protein 43
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPA3 replication protein A3, 14kDa
RPL36 ribosomal protein L36
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RRAGD Ras-related GTP binding D
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
RUNX3 runt-related transcription factor 3
S100A2 S100 calcium binding protein A2
S100A7 S100 calcium binding protein A7
S100B S100 calcium binding protein B
SCAND1 SCAN domain containing 1
SCG2 secretogranin II
SCML1 sex comb on midleg-like 1 (Drosophila)
SDC2 syndecan 2
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SFRP1 secreted frizzled-related protein 1
SGCE sarcoglycan, epsilon
SH3BP4 SH3-domain binding protein 4
SKAP2 src kinase associated phosphoprotein 2
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC38A2 solute carrier family 38, member 2
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SMAD3 SMAD family member 3
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SNX7 sorting nexin 7
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SOX11 SRY (sex determining region Y)-box 11
SPINK1 serine peptidase inhibitor, Kazal type 1
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SPON2 spondin 2, extracellular matrix protein
SPRR1A small proline-rich protein 1A
SPRR1B small proline-rich protein 1B
SPRR2B small proline-rich protein 2B
SPRY2 sprouty homolog 2 (Drosophila)
SRPX sushi-repeat containing protein, X-linked
SRSF1 serine/arginine-rich splicing factor 1
SRSF5 serine/arginine-rich splicing factor 5
STC1 stanniocalcin 1
STK17A serine/threonine kinase 17a
SULF1 sulfatase 1
TACSTD2 tumor-associated calcium signal transducer 2
TCF4 transcription factor 4
TDRD12 tudor domain containing 12
TEX10 testis expressed 10
TF transferrin
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TFF1 trefoil factor 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TFRC transferrin receptor
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TGFBI transforming growth factor, beta-induced, 68kDa
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBS1 thrombospondin 1
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TKTL1 transketolase-like 1
TM4SF1 transmembrane 4 L six family member 1
TM4SF4 transmembrane 4 L six family member 4
TMEM106B transmembrane protein 106B
TMEM165 transmembrane protein 165
TMEM2 transmembrane protein 2
TMPO thymopoietin
TNC tenascin C
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TOX3 TOX high mobility group box family member 3
TRD T cell receptor delta locus
TSPAN12 tetraspanin 12
TSPAN4 tetraspanin 4
TSPAN8 tetraspanin 8
TUBB2A tubulin, beta 2A class IIa
TUBB2B tubulin, beta 2B class IIb
TUBB6 tubulin, beta 6 class V
TXLNA taxilin alpha
TYRP1 tyrosinase-related protein 1
UBE2E3 ubiquitin-conjugating enzyme E2E 3
UGCG UDP-glucose ceramide glucosyltransferase
USP22 ubiquitin specific peptidase 22
VAT1 vesicle amine transport 1
VCAM1 vascular cell adhesion molecule 1
VCAN versican
VGLL4 vestigial-like family member 4
VSNL1 visinin-like 1
ZFP36L1 ZFP36 ring finger protein-like 1
ZFP36L2 ZFP36 ring finger protein-like 2
ZHX2 zinc fingers and homeoboxes 2
ZIC1 Zic family member 1