BRD-A19248578_L5288-1MG_SKB_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

40 genes differentially expressed following the BRD-A19248578_L5288-1MG_SKB_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ADGRF5 adhesion G protein-coupled receptor F5
CD163 CD163 molecule
COL15A1 collagen, type XV, alpha 1
CXCL14 chemokine (C-X-C motif) ligand 14
DPP4 dipeptidyl-peptidase 4
DPYD dihydropyrimidine dehydrogenase
FABP4 fatty acid binding protein 4, adipocyte
HMOX1 heme oxygenase 1
MAN1A1 mannosidase, alpha, class 1A, member 1
MAOA monoamine oxidase A
NPC1 Niemann-Pick disease, type C1
PCSK1 proprotein convertase subtilisin/kexin type 1
RHOBTB3 Rho-related BTB domain containing 3
SOD2 superoxide dismutase 2, mitochondrial
SPARCL1 SPARC-like 1 (hevin)
TFPI2 tissue factor pathway inhibitor 2

decreased expression

Symbol Name
ANXA3 annexin A3
CAV2 caveolin 2
CTGF connective tissue growth factor
CYR61 cysteine-rich, angiogenic inducer, 61
DKK1 dickkopf WNT signaling pathway inhibitor 1
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ERBB2 erb-b2 receptor tyrosine kinase 2
FN1 fibronectin 1
FOLR1 folate receptor 1 (adult)
GSTP1 glutathione S-transferase pi 1
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
LOX lysyl oxidase
MARCKS myristoylated alanine-rich protein kinase C substrate
PTX3 pentraxin 3, long
RCAN1 regulator of calcineurin 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
STC2 stanniocalcin 2
TFF1 trefoil factor 1
THBS1 thrombospondin 1
TPM1 tropomyosin 1 (alpha)
TSPAN13 tetraspanin 13