BRD-A19248578_L5288-1MG_PHH_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

33 genes differentially expressed following the BRD-A19248578_L5288-1MG_PHH_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
HP haptoglobin
LCN2 lipocalin 2
MAN2A1 mannosidase, alpha, class 2A, member 1
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta)
PBX3 pre-B-cell leukemia homeobox 3
RGCC regulator of cell cycle
ZNF217 zinc finger protein 217

decreased expression

Symbol Name
BEX1 brain expressed, X-linked 1
CCNA2 cyclin A2
CCND1 cyclin D1
CDC20 cell division cycle 20
COL3A1 collagen, type III, alpha 1
CPM carboxypeptidase M
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
KRT14 keratin 14, type I
KRT19 keratin 19, type I
KRT5 keratin 5, type II
LUM lumican
NPY1R neuropeptide Y receptor Y1
NR0B1 nuclear receptor subfamily 0, group B, member 1
PROM1 prominin 1
PSPH phosphoserine phosphatase
RPL37A ribosomal protein L37a
RPS11 ribosomal protein S11
SLIRP SRA stem-loop interacting RNA binding protein
TUSC3 tumor suppressor candidate 3