BRD-A19248578_L5288-1MG_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

41 genes differentially expressed following the BRD-A19248578_L5288-1MG_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C3 aldo-keto reductase family 1, member C3
BMP2 bone morphogenetic protein 2
CA2 carbonic anhydrase II
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CLIC4 chloride intracellular channel 4
DDIT4 DNA-damage-inducible transcript 4
EFHD1 EF-hand domain family, member D1
EZR ezrin
FOXO4 forkhead box O4
GDF15 growth differentiation factor 15
H1F0 H1 histone family, member 0
HECA headcase homolog (Drosophila)
HMOX1 heme oxygenase 1
ITM2C integral membrane protein 2C
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MMD monocyte to macrophage differentiation-associated
MMP1 matrix metallopeptidase 1
MMP11 matrix metallopeptidase 11
NEU1 sialidase 1 (lysosomal sialidase)
NQO1 NAD(P)H dehydrogenase, quinone 1
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PLAU plasminogen activator, urokinase
PLIN2 perilipin 2
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
RSRP1 arginine/serine-rich protein 1
SAT1 spermidine/spermine N1-acetyltransferase 1
SQSTM1 sequestosome 1
STX1A syntaxin 1A (brain)
TP53BP2 tumor protein p53 binding protein 2
VGLL4 vestigial-like family member 4
WIPI1 WD repeat domain, phosphoinositide interacting 1

decreased expression

Symbol Name
CCND1 cyclin D1
FHL2 four and a half LIM domains 2
FOSL1 FOS-like antigen 1
GTPBP8 GTP-binding protein 8 (putative)
IGFBP3 insulin-like growth factor binding protein 3
KRT15 keratin 15, type I
KRT5 keratin 5, type II
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
ZBED2 zinc finger, BED-type containing 2