BRD-A19248578_L5288-1MG_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

22 genes differentially expressed following the BRD-A19248578_L5288-1MG_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AFF1 AF4/FMR2 family, member 1
AKAP13 A kinase (PRKA) anchor protein 13
BST2 bone marrow stromal cell antigen 2
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
FOXO4 forkhead box O4
HECA headcase homolog (Drosophila)
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
LEF1 lymphoid enhancer-binding factor 1
MYO10 myosin X
NPC1 Niemann-Pick disease, type C1
RAB11FIP1 RAB11 family interacting protein 1 (class I)
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
TBC1D4 TBC1 domain family, member 4
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
WDTC1 WD and tetratricopeptide repeats 1

decreased expression

Symbol Name
ADIRF adipogenesis regulatory factor
COL3A1 collagen, type III, alpha 1
CYC1 cytochrome c-1
EIF5 eukaryotic translation initiation factor 5
MRPL15 mitochondrial ribosomal protein L15
PRR7 proline rich 7 (synaptic)