BRD-A19248578_L5288-1MG_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

38 genes differentially expressed following the BRD-A19248578_L5288-1MG_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CCNG2 cyclin G2
CTSA cathepsin A
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FAM102A family with sequence similarity 102, member A
FOXG1 forkhead box G1
FOXO4 forkhead box O4
IGL immunoglobulin lambda locus
MMP1 matrix metallopeptidase 1
NPC1 Niemann-Pick disease, type C1
PALLD palladin, cytoskeletal associated protein
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
POR P450 (cytochrome) oxidoreductase
PTN pleiotrophin
SEPT6 septin 6
STX1A syntaxin 1A (brain)
TIAM1 T-cell lymphoma invasion and metastasis 1
WIPI1 WD repeat domain, phosphoinositide interacting 1

decreased expression

Symbol Name
ATF1 activating transcription factor 1
BDH1 3-hydroxybutyrate dehydrogenase, type 1
CCND1 cyclin D1
DKK1 dickkopf WNT signaling pathway inhibitor 1
EXOSC4 exosome component 4
FAM57A family with sequence similarity 57, member A
FHL2 four and a half LIM domains 2
FOSL1 FOS-like antigen 1
GSAP gamma-secretase activating protein
HMGA2 high mobility group AT-hook 2
LCMT2 leucine carboxyl methyltransferase 2
MOK MOK protein kinase
MYC v-myc avian myelocytomatosis viral oncogene homolog
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NME4 NME/NM23 nucleoside diphosphate kinase 4
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PRSS23 protease, serine, 23
SNRPE small nuclear ribonucleoprotein polypeptide E
THY1 Thy-1 cell surface antigen