BRD-A19195498_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

46 genes differentially expressed following the BRD-A19195498_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATHL1 ATH1, acid trehalase-like 1 (yeast)
CLPTM1 cleft lip and palate associated transmembrane protein 1
CXCL13 chemokine (C-X-C motif) ligand 13
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DHCR24 24-dehydrocholesterol reductase
DHCR7 7-dehydrocholesterol reductase
EBP emopamil binding protein (sterol isomerase)
FADS1 fatty acid desaturase 1
FADS2 fatty acid desaturase 2
FDPS farnesyl diphosphate synthase
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GLRX glutaredoxin (thioltransferase)
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGLJ3 immunoglobulin lambda joining 3
INSIG1 insulin induced gene 1
KRT14 keratin 14, type I
LDLR low density lipoprotein receptor
LTF lactotransferrin
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MSMO1 methylsterol monooxygenase 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
PRUNE2 prune homolog 2 (Drosophila)
RNF167 ring finger protein 167
RSRP1 arginine/serine-rich protein 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SQLE squalene epoxidase
TPD52 tumor protein D52
TPP1 tripeptidyl peptidase I

decreased expression

Symbol Name
DUOX2 dual oxidase 2
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ITM2A integral membrane protein 2A
MFAP3L microfibrillar-associated protein 3-like
MXRA7 matrix-remodelling associated 7
PCP4 Purkinje cell protein 4
RGS2 regulator of G-protein signaling 2
SCGB2A1 secretoglobin, family 2A, member 1
TPD52L1 tumor protein D52-like 1
TUSC3 tumor suppressor candidate 3