BRD-A18763547_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

19 genes differentially expressed following the BRD-A18763547_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
BHLHE40 basic helix-loop-helix family, member e40
CHIC2 cysteine-rich hydrophobic domain 2
COCH cochlin
EFNA1 ephrin-A1
FADS1 fatty acid desaturase 1
HSPA13 heat shock protein 70kDa family, member 13
INSIG1 insulin induced gene 1
LDLR low density lipoprotein receptor
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
SCD stearoyl-CoA desaturase (delta-9-desaturase)
TRIB3 tribbles pseudokinase 3
TSC22D3 TSC22 domain family, member 3
VCAN versican

decreased expression

Symbol Name
CCND1 cyclin D1
CLU clusterin
DKK1 dickkopf WNT signaling pathway inhibitor 1
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
TMEM14A transmembrane protein 14A