BRD-A18620900_ESTRIOL_HA1E_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

106 genes differentially expressed following the BRD-A18620900_ESTRIOL_HA1E_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAT1 adenosine deaminase, tRNA-specific 1
BLNK B-cell linker
BMP4 bone morphogenetic protein 4
CAPG capping protein (actin filament), gelsolin-like
CCL5 chemokine (C-C motif) ligand 5
CCNA1 cyclin A1
CD8A CD8a molecule
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CRABP1 cellular retinoic acid binding protein 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL9 chemokine (C-X-C motif) ligand 9
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GZMK granzyme K (granzyme 3; tryptase II)
HBB hemoglobin, beta
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IDO1 indoleamine 2,3-dioxygenase 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IL7R interleukin 7 receptor
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
KRT18 keratin 18, type I
LAMP3 lysosomal-associated membrane protein 3
LCK LCK proto-oncogene, Src family tyrosine kinase
LDOC1 leucine zipper, down-regulated in cancer 1
LOC100505650 uncharacterized LOC100505650
LPAR6 lysophosphatidic acid receptor 6
LYZ lysozyme
MEIS2 Meis homeobox 2
MMP12 matrix metallopeptidase 12
MNDA myeloid cell nuclear differentiation antigen
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NEB nebulin
NEFL neurofilament, light polypeptide
P3H2 prolyl 3-hydroxylase 2
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PRKCQ protein kinase C, theta
PTPRC protein tyrosine phosphatase, receptor type, C
SLC38A1 solute carrier family 38, member 1
TBC1D31 TBC1 domain family, member 31
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TPM2 tropomyosin 2 (beta)
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3)
VEGFA vascular endothelial growth factor A
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ADD3 adducin 3 (gamma)
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
APOD apolipoprotein D
BST2 bone marrow stromal cell antigen 2
CD59 CD59 molecule, complement regulatory protein
CHPT1 choline phosphotransferase 1
COL14A1 collagen, type XIV, alpha 1
COL9A3 collagen, type IX, alpha 3
COMP cartilage oligomeric matrix protein
CP ceruloplasmin (ferroxidase)
CRY1 cryptochrome circadian clock 1
CTSK cathepsin K
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CYTL1 cytokine-like 1
DUSP22 dual specificity phosphatase 22
E2F2 E2F transcription factor 2
EGR3 early growth response 3
EMP1 epithelial membrane protein 1
FCGBP Fc fragment of IgG binding protein
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
GLDC glycine dehydrogenase (decarboxylating)
HAL histidine ammonia-lyase
HOMER1 homer scaffolding protein 1
IFI6 interferon, alpha-inducible protein 6
ING3 inhibitor of growth family, member 3
KRT14 keratin 14, type I
LCN2 lipocalin 2
LYPLA1 lysophospholipase I
MAGEA1 melanoma antigen family A1
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAOB monoamine oxidase B
MARCKS myristoylated alanine-rich protein kinase C substrate
MLF1 myeloid leukemia factor 1
NAMPT nicotinamide phosphoribosyltransferase
NOTCH2 notch 2
PCOLCE procollagen C-endopeptidase enhancer
PI3 peptidase inhibitor 3, skin-derived
PLAT plasminogen activator, tissue
PLTP phospholipid transfer protein
PPIC peptidylprolyl isomerase C (cyclophilin C)
PRDX2 peroxiredoxin 2
PRDX4 peroxiredoxin 4
PRSS3 protease, serine, 3
RCAN1 regulator of calcineurin 1
RPL27A ribosomal protein L27a
RPS11 ribosomal protein S11
S100A7 S100 calcium binding protein A7
SCRG1 stimulator of chondrogenesis 1
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SORBS1 sorbin and SH3 domain containing 1
SPINK1 serine peptidase inhibitor, Kazal type 1
SRPX sushi-repeat containing protein, X-linked
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TNC tenascin C
TYMS thymidylate synthetase