BRD-A18579359_wiskostatin_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

86 genes differentially expressed following the BRD-A18579359_wiskostatin_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADCY1 adenylate cyclase 1 (brain)
ALDOC aldolase C, fructose-bisphosphate
BACE2 beta-site APP-cleaving enzyme 2
BID BH3 interacting domain death agonist
CD24 CD24 molecule
CD36 CD36 molecule (thrombospondin receptor)
COLEC12 collectin sub-family member 12
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DHCR7 7-dehydrocholesterol reductase
EBP emopamil binding protein (sterol isomerase)
ELOVL6 ELOVL fatty acid elongase 6
FAM171A1 family with sequence similarity 171, member A1
FGR FGR proto-oncogene, Src family tyrosine kinase
FHL1 four and a half LIM domains 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GAL galanin/GMAP prepropeptide
GLIPR1 GLI pathogenesis-related 1
GREB1 growth regulation by estrogen in breast cancer 1
HBD hemoglobin, delta
HDGFRP3 hepatoma-derived growth factor, related protein 3
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
INSIG1 insulin induced gene 1
ISL1 ISL LIM homeobox 1
LDLR low density lipoprotein receptor
LEF1 lymphoid enhancer-binding factor 1
MSMO1 methylsterol monooxygenase 1
OLFM4 olfactomedin 4
OPN3 opsin 3
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PXDN peroxidasin
SFRP1 secreted frizzled-related protein 1
TFF1 trefoil factor 1
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TWIST1 twist family bHLH transcription factor 1
VIM vimentin
ZEB1 zinc finger E-box binding homeobox 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACD adrenocortical dysplasia homolog (mouse)
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
AQP3 aquaporin 3 (Gill blood group)
CCNB2 cyclin B2
CCNF cyclin F
CD79A CD79a molecule, immunoglobulin-associated alpha
CPA3 carboxypeptidase A3 (mast cell)
CXCL13 chemokine (C-X-C motif) ligand 13
DCN decorin
DKK3 dickkopf WNT signaling pathway inhibitor 3
EIF5 eukaryotic translation initiation factor 5
EMP2 epithelial membrane protein 2
EPAS1 endothelial PAS domain protein 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
FOS FBJ murine osteosarcoma viral oncogene homolog
GRWD1 glutamate-rich WD repeat containing 1
HAT1 histone acetyltransferase 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HOPX HOP homeobox
HOXA5 homeobox A5
HOXB7 homeobox B7
IFI44L interferon-induced protein 44-like
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGHM immunoglobulin heavy constant mu
ISG15 ISG15 ubiquitin-like modifier
ITGB1BP1 integrin beta 1 binding protein 1
KRT19 keratin 19, type I
KRT7 keratin 7, type II
LAMP3 lysosomal-associated membrane protein 3
MALL mal, T-cell differentiation protein-like
MET MET proto-oncogene, receptor tyrosine kinase
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
PIH1D1 PIH1 domain containing 1
PLK2 polo-like kinase 2
RHOBTB3 Rho-related BTB domain containing 3
RPA3 replication protein A3, 14kDa
S100A10 S100 calcium binding protein A10
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
TACSTD2 tumor-associated calcium signal transducer 2
TBCB tubulin folding cofactor B
TEX10 testis expressed 10
TNNT1 troponin T type 1 (skeletal, slow)
TSPAN12 tetraspanin 12