BRD-A18579359_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

60 genes differentially expressed following the BRD-A18579359_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAT2 acetyl-CoA acetyltransferase 2
ACPP acid phosphatase, prostate
ARG2 arginase 2
ARMCX1 armadillo repeat containing, X-linked 1
BEX4 brain expressed, X-linked 4
CD24 CD24 molecule
CD47 CD47 molecule
CD9 CD9 molecule
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLCA4 chloride channel accessory 4
CSRP1 cysteine and glycine-rich protein 1
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
EZR ezrin
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FDPS farnesyl diphosphate synthase
GAREM GRB2 associated, regulator of MAPK1
GDF15 growth differentiation factor 15
GREB1 growth regulation by estrogen in breast cancer 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HSPA12A heat shock 70kDa protein 12A
IDI1 isopentenyl-diphosphate delta isomerase 1
INSIG1 insulin induced gene 1
LDLR low density lipoprotein receptor
LMO2 LIM domain only 2 (rhombotin-like 1)
MALL mal, T-cell differentiation protein-like
MSMO1 methylsterol monooxygenase 1
NPTX2 neuronal pentraxin II
PLAT plasminogen activator, tissue
QPCT glutaminyl-peptide cyclotransferase
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SC5D sterol-C5-desaturase
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCUBE2 signal peptide, CUB domain, EGF-like 2
SFN stratifin
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SQLE squalene epoxidase
SYT1 synaptotagmin I
TIMP3 TIMP metallopeptidase inhibitor 3
VAT1 vesicle amine transport 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
C6ORF48 chromosome 6 open reading frame 48
CLDN18 claudin 18
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
FMO2 flavin containing monooxygenase 2 (non-functional)
GADD45B growth arrest and DNA-damage-inducible, beta
KIF14 kinesin family member 14
KYNU kynureninase
MT1H metallothionein 1H
MT1X metallothionein 1X
MT2A metallothionein 2A
NEK2 NIMA-related kinase 2
PEG10 paternally expressed 10
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
TOP2A topoisomerase (DNA) II alpha 170kDa
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative)