BRD-A18579359_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

75 genes differentially expressed following the BRD-A18579359_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ABHD4 abhydrolase domain containing 4
AKR1C3 aldo-keto reductase family 1, member C3
ALCAM activated leukocyte cell adhesion molecule
ALOX15B arachidonate 15-lipoxygenase, type B
APOC1 apolipoprotein C-I
ATP9A ATPase, class II, type 9A
BEX1 brain expressed, X-linked 1
C14ORF1 chromosome 14 open reading frame 1
CCNG2 cyclin G2
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHMP4A charged multivesicular body protein 4A
DDIT4 DNA-damage-inducible transcript 4
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DHCR7 7-dehydrocholesterol reductase
EBP emopamil binding protein (sterol isomerase)
ERBB3 erb-b2 receptor tyrosine kinase 3
FADS1 fatty acid desaturase 1
FASN fatty acid synthase
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FDPS farnesyl diphosphate synthase
GNAS GNAS complex locus
GPC3 glypican 3
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MSMO1 methylsterol monooxygenase 1
PXDN peroxidasin
S100A14 S100 calcium binding protein A14
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SORBS3 sorbin and SH3 domain containing 3
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SQLE squalene epoxidase
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TF transferrin
TIMP3 TIMP metallopeptidase inhibitor 3
TKT transketolase
VGLL4 vestigial-like family member 4
VIM vimentin
WDR61 WD repeat domain 61
ZNF185 zinc finger protein 185 (LIM domain)

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANXA10 annexin A10
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
CDC42 cell division cycle 42
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8
COPS7A COP9 signalosome subunit 7A
CXCL8 chemokine (C-X-C motif) ligand 8
CYR61 cysteine-rich, angiogenic inducer, 61
DEFA4 defensin, alpha 4, corticostatin
DUSP6 dual specificity phosphatase 6
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EREG epiregulin
F2RL1 coagulation factor II (thrombin) receptor-like 1
F3 coagulation factor III (thromboplastin, tissue factor)
FOSL1 FOS-like antigen 1
GLIPR1 GLI pathogenesis-related 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ICAM1 intercellular adhesion molecule 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IER3 immediate early response 3
KCTD12 potassium channel tetramerization domain containing 12
LAPTM4B lysosomal protein transmembrane 4 beta
LCN2 lipocalin 2
MMP9 matrix metallopeptidase 9
NFIB nuclear factor I/B
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
RNF167 ring finger protein 167
STEAP1 six transmembrane epithelial antigen of the prostate 1
TACSTD2 tumor-associated calcium signal transducer 2
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
XIST X inactive specific transcript (non-protein coding)