BRD-A18497530_EI-293_ASC_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

249 genes differentially expressed following the BRD-A18497530_EI-293_ASC_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ADD3 adducin 3 (gamma)
ADGRF5 adhesion G protein-coupled receptor F5
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ANOS1 anosmin 1
AQP1 aquaporin 1 (Colton blood group)
ASPN asporin
ATHL1 ATH1, acid trehalase-like 1 (yeast)
AZU1 azurocidin 1
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BGN biglycan
CADM1 cell adhesion molecule 1
CALD1 caldesmon 1
CALU calumenin
CDC42 cell division cycle 42
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CEP70 centrosomal protein 70kDa
CERS6 ceramide synthase 6
CKB creatine kinase, brain
CLC Charcot-Leyden crystal galectin
CLEC2B C-type lectin domain family 2, member B
CLU clusterin
COL1A1 collagen, type I, alpha 1
COL3A1 collagen, type III, alpha 1
COL4A5 collagen, type IV, alpha 5
COL4A6 collagen, type IV, alpha 6
COL5A2 collagen, type V, alpha 2
CPE carboxypeptidase E
CTSZ cathepsin Z
CXADR coxsackie virus and adenovirus receptor
CXCL8 chemokine (C-X-C motif) ligand 8
DEFA4 defensin, alpha 4, corticostatin
DKK3 dickkopf WNT signaling pathway inhibitor 3
EDNRA endothelin receptor type A
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGR1 early growth response 1
EIF5A eukaryotic translation initiation factor 5A
ELANE elastase, neutrophil expressed
EXPH5 exophilin 5
F2R coagulation factor II (thrombin) receptor
FLRT2 fibronectin leucine rich transmembrane protein 2
FN1 fibronectin 1
FRZB frizzled-related protein
GBP1 guanylate binding protein 1, interferon-inducible
GLIPR1 GLI pathogenesis-related 1
GLT8D2 glycosyltransferase 8 domain containing 2
GUSBP3 glucuronidase, beta pseudogene 3
HEG1 heart development protein with EGF-like domains 1
HIP1 huntingtin interacting protein 1
HIPK1 homeodomain interacting protein kinase 1
HIST1H2BC histone cluster 1, H2bc
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IER3 immediate early response 3
IGFBP3 insulin-like growth factor binding protein 3
ITM2A integral membrane protein 2A
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KRT4 keratin 4, type II
KRT5 keratin 5, type II
LAMP3 lysosomal-associated membrane protein 3
LCN2 lipocalin 2
LPPR4 lipid phosphate phosphatase-related protein type 4
LRRC17 leucine rich repeat containing 17
LTBP1 latent transforming growth factor beta binding protein 1
LUM lumican
MATN2 matrilin 2
MEIS1 Meis homeobox 1
MEIS2 Meis homeobox 2
MMP9 matrix metallopeptidase 9
MN1 meningioma (disrupted in balanced translocation) 1
MXI1 MAX interactor 1, dimerization protein
MXRA5 matrix-remodelling associated 5
NID1 nidogen 1
NR2F1 nuclear receptor subfamily 2, group F, member 1
PRKCI protein kinase C, iota
PRTN3 proteinase 3
PTHLH parathyroid hormone-like hormone
PTN pleiotrophin
RGS5 regulator of G-protein signaling 5
RPL31 ribosomal protein L31
S100A9 S100 calcium binding protein A9
SCG2 secretogranin II
SCG5 secretogranin V
SEPP1 selenoprotein P, plasma, 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLPI secretory leukocyte peptidase inhibitor
SPARCL1 SPARC-like 1 (hevin)
STC1 stanniocalcin 1
TIMP3 TIMP metallopeptidase inhibitor 3
TKTL1 transketolase-like 1
TSPAN7 tetraspanin 7
TTC3 tetratricopeptide repeat domain 3
TUSC3 tumor suppressor candidate 3
VTCN1 V-set domain containing T cell activation inhibitor 1
WIF1 WNT inhibitory factor 1
WSB1 WD repeat and SOCS box containing 1
WT1 Wilms tumor 1

decreased expression

Symbol Name
ACACA acetyl-CoA carboxylase alpha
ACLY ATP citrate lyase
ACSL1 acyl-CoA synthetase long-chain family member 1
ADGRG2 adhesion G protein-coupled receptor G2
AHNAK AHNAK nucleoprotein
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ATF5 activating transcription factor 5
ATMIN ATM interactor
BAG3 BCL2-associated athanogene 3
BLCAP bladder cancer associated protein
BLVRA biliverdin reductase A
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BUB3 BUB3 mitotic checkpoint protein
C14ORF166 chromosome 14 open reading frame 166
CAB39 calcium binding protein 39
CALML5 calmodulin-like 5
CCDC109B coiled-coil domain containing 109B
CCNB2 cyclin B2
CD163 CD163 molecule
CD164 CD164 molecule, sialomucin
CD79A CD79a molecule, immunoglobulin-associated alpha
CDC20 cell division cycle 20
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CLTA clathrin, light chain A
CLTC clathrin, heavy chain (Hc)
COA3 cytochrome c oxidase assembly factor 3
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
DDIT4 DNA-damage-inducible transcript 4
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DRG1 developmentally regulated GTP binding protein 1
DUSP6 dual specificity phosphatase 6
EFR3A EFR3 homolog A (S. cerevisiae)
EIF6 eukaryotic translation initiation factor 6
ELOVL1 ELOVL fatty acid elongase 1
ELOVL6 ELOVL fatty acid elongase 6
FABP7 fatty acid binding protein 7, brain
FAM57A family with sequence similarity 57, member A
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FHL2 four and a half LIM domains 2
FOSL1 FOS-like antigen 1
FOXJ3 forkhead box J3
FOXO3 forkhead box O3
GDF15 growth differentiation factor 15
GLRX glutaredoxin (thioltransferase)
GLS glutaminase
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GRWD1 glutamate-rich WD repeat containing 1
GSPT2 G1 to S phase transition 2
HK1 hexokinase 1
HMGB2 high mobility group box 2
HMOX1 heme oxygenase 1
HOXA10 homeobox A10
HSPA8 heat shock 70kDa protein 8
IDI1 isopentenyl-diphosphate delta isomerase 1
IGFBP4 insulin-like growth factor binding protein 4
IMP3 IMP3, U3 small nucleolar ribonucleoprotein
INSIG1 insulin induced gene 1
IRS2 insulin receptor substrate 2
JAK1 Janus kinase 1
JMJD6 jumonji domain containing 6
KIAA0922 KIAA0922
KIAA1033 KIAA1033
KRT10 keratin 10, type I
LAT2 linker for activation of T cells family, member 2
LBR lamin B receptor
LDLR low density lipoprotein receptor
LINC00341 long intergenic non-protein coding RNA 341
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LTF lactotransferrin
MACF1 microtubule-actin crosslinking factor 1
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MKNK2 MAP kinase interacting serine/threonine kinase 2
MPRIP myosin phosphatase Rho interacting protein
MTCL1 microtubule crosslinking factor 1
MVP major vault protein
NGDN neuroguidin, EIF4E binding protein
NMI N-myc (and STAT) interactor
NNMT nicotinamide N-methyltransferase
NOP56 NOP56 ribonucleoprotein
NPY1R neuropeptide Y receptor Y1
NRIP1 nuclear receptor interacting protein 1
NRN1 neuritin 1
PACSIN2 protein kinase C and casein kinase substrate in neurons 2
PANK2 pantothenate kinase 2
PCNA proliferating cell nuclear antigen
PHF20 PHD finger protein 20
PLA2G16 phospholipase A2, group XVI
PNP purine nucleoside phosphorylase
PPARG peroxisome proliferator-activated receptor gamma
PRKCDBP protein kinase C, delta binding protein
PRPF4B pre-mRNA processing factor 4B
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
PUF60 poly-U binding splicing factor 60KDa
PWP1 PWP1 homolog (S. cerevisiae)
RAE1 ribonucleic acid export 1
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RGS2 regulator of G-protein signaling 2
RNMT RNA (guanine-7-) methyltransferase
RNPS1 RNA binding protein S1, serine-rich domain
RPL36AL ribosomal protein L36a-like
RPS27L ribosomal protein S27-like
RRAGC Ras-related GTP binding C
RTCB RNA 2',3'-cyclic phosphate and 5'-OH ligase
SACM1L SAC1 suppressor of actin mutations 1-like (yeast)
SAP30 Sin3A-associated protein, 30kDa
SCAND1 SCAN domain containing 1
SEC24B SEC24 family member B
SEPT9 septin 9
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SNRPB small nuclear ribonucleoprotein polypeptides B and B1
SNRPB2 small nuclear ribonucleoprotein polypeptide B
SOCS1 suppressor of cytokine signaling 1
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
SYNM synemin, intermediate filament protein
TBC1D4 TBC1 domain family, member 4
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast)
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TJP2 tight junction protein 2
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMX4 thioredoxin-related transmembrane protein 4
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TRAM2 translocation associated membrane protein 2
TRAPPC3 trafficking protein particle complex 3
TSC22D3 TSC22 domain family, member 3
TSKU tsukushi, small leucine rich proteoglycan
TSPYL5 TSPY-like 5
TXLNA taxilin alpha
TXNDC9 thioredoxin domain containing 9
TXNIP thioredoxin interacting protein
TXNRD1 thioredoxin reductase 1
UBAP2L ubiquitin associated protein 2-like
USP22 ubiquitin specific peptidase 22
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)
VCP valosin containing protein
WTAP Wilms tumor 1 associated protein
XBP1 X-box binding protein 1
YBX3 Y box binding protein 3