BRD-A18419789_Etoposide_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

72 genes differentially expressed following the BRD-A18419789_Etoposide_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
AKR1C2 aldo-keto reductase family 1, member C2
ARMCX1 armadillo repeat containing, X-linked 1
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
BTG2 BTG family, member 2
CADM1 cell adhesion molecule 1
CECR1 cat eye syndrome chromosome region, candidate 1
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
GFPT2 glutamine-fructose-6-phosphate transaminase 2
HCP5 HLA complex P5 (non-protein coding)
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-F major histocompatibility complex, class I, F
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGHD immunoglobulin heavy constant delta
IL32 interleukin 32
INSM1 insulinoma-associated 1
LMO4 LIM domain only 4
MARCH3 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase
MGP matrix Gla protein
NLRP2 NLR family, pyrin domain containing 2
PBX1 pre-B-cell leukemia homeobox 1
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1
PNRC1 proline-rich nuclear receptor coactivator 1
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PYCARD PYD and CARD domain containing
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SERINC3 serine incorporator 3
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TF transferrin
TKTL1 transketolase-like 1

decreased expression

Symbol Name
ACSL1 acyl-CoA synthetase long-chain family member 1
ADGRE5 adhesion G protein-coupled receptor E5
ALCAM activated leukocyte cell adhesion molecule
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ATP5I ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E
CCND1 cyclin D1
CD320 CD320 molecule
CDC20 cell division cycle 20
CRISP3 cysteine-rich secretory protein 3
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DHCR24 24-dehydrocholesterol reductase
FGG fibrinogen gamma chain
GLB1L2 galactosidase, beta 1-like 2
GNL3 guanine nucleotide binding protein-like 3 (nucleolar)
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
KIF20A kinesin family member 20A
LAMA3 laminin, alpha 3
LUC7L3 LUC7-like 3 (S. cerevisiae)
LY6E lymphocyte antigen 6 complex, locus E
MBNL1 muscleblind-like splicing regulator 1
MSMO1 methylsterol monooxygenase 1
MTA1 metastasis associated 1
MTDH metadherin
MYC v-myc avian myelocytomatosis viral oncogene homolog
NME1 NME/NM23 nucleoside diphosphate kinase 1
NMU neuromedin U
OXTR oxytocin receptor
PLK1 polo-like kinase 1
PYCR1 pyrroline-5-carboxylate reductase 1
RPIA ribose 5-phosphate isomerase A
SLCO1B3 solute carrier organic anion transporter family, member 1B3
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
UBE2S ubiquitin-conjugating enzyme E2S