BRD-A18419789_Etoposide_HT29_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

97 genes differentially expressed following the BRD-A18419789_Etoposide_HT29_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
C1S complement component 1, s subcomponent
CAPG capping protein (actin filament), gelsolin-like
CDK2 cyclin-dependent kinase 2
CFB complement factor B
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL13 chemokine (C-X-C motif) ligand 13
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
FAM129A family with sequence similarity 129, member A
FN1 fibronectin 1
GUSBP11 glucuronidase, beta pseudogene 11
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HES1 hes family bHLH transcription factor 1
HILPDA hypoxia inducible lipid droplet-associated
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-F major histocompatibility complex, class I, F
HLA-G major histocompatibility complex, class I, G
HOPX HOP homeobox
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGHMBP2 immunoglobulin mu binding protein 2
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
IGLJ3 immunoglobulin lambda joining 3
IGLV2-23 immunoglobulin lambda variable 2-23
ISG15 ISG15 ubiquitin-like modifier
KIAA0101 KIAA0101
KRT17 keratin 17, type I
KRT7 keratin 7, type II
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MYH10 myosin, heavy chain 10, non-muscle
MZB1 marginal zone B and B1 cell-specific protein
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NMI N-myc (and STAT) interactor
NR4A3 nuclear receptor subfamily 4, group A, member 3
PDE4B phosphodiesterase 4B, cAMP-specific
PEA15 phosphoprotein enriched in astrocytes 15
PIP prolactin-induced protein
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
RSAD2 radical S-adenosyl methionine domain containing 2
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SIK1 salt-inducible kinase 1
SOD2 superoxide dismutase 2, mitochondrial
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TGM2 transglutaminase 2
TM4SF1 transmembrane 4 L six family member 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10

decreased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AOX1 aldehyde oxidase 1
ATP10B ATPase, class V, type 10B
AURKA aurora kinase A
BMP4 bone morphogenetic protein 4
C9ORF3 chromosome 9 open reading frame 3
CFD complement factor D (adipsin)
CLC Charcot-Leyden crystal galectin
CRISP3 cysteine-rich secretory protein 3
CXCL3 chemokine (C-X-C motif) ligand 3
DACH1 dachshund family transcription factor 1
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DEFA4 defensin, alpha 4, corticostatin
DKK1 dickkopf WNT signaling pathway inhibitor 1
ELANE elastase, neutrophil expressed
EXOSC4 exosome component 4
FAM171A1 family with sequence similarity 171, member A1
FOLR1 folate receptor 1 (adult)
GATA2 GATA binding protein 2
GATA3 GATA binding protein 3
GATA6 GATA binding protein 6
KIF20A kinesin family member 20A
LAMP5 lysosomal-associated membrane protein family, member 5
LCN2 lipocalin 2
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
MAN1A1 mannosidase, alpha, class 1A, member 1
MPO myeloperoxidase
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
NCAM1 neural cell adhesion molecule 1
NHP2 NHP2 ribonucleoprotein
NOSIP nitric oxide synthase interacting protein
OLFM4 olfactomedin 4
PF4 platelet factor 4
PLK1 polo-like kinase 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PUF60 poly-U binding splicing factor 60KDa
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
S100A12 S100 calcium binding protein A12
S100P S100 calcium binding protein P
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
TIAM1 T-cell lymphoma invasion and metastasis 1
TRIM2 tripartite motif containing 2