BRD-A18328003_GDC-0980_SKBR3_3_h_0.12_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

73 genes differentially expressed following the BRD-A18328003_GDC-0980_SKBR3_3_h_0.12_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTA2 actin, alpha 2, smooth muscle, aorta
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
BHLHE40 basic helix-loop-helix family, member e40
CD36 CD36 molecule (thrombospondin receptor)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
DOK5 docking protein 5
ERBB3 erb-b2 receptor tyrosine kinase 3
FAM13A family with sequence similarity 13, member A
FAS Fas cell surface death receptor
FLRT2 fibronectin leucine rich transmembrane protein 2
FOLR1 folate receptor 1 (adult)
GPNMB glycoprotein (transmembrane) nmb
GRB7 growth factor receptor-bound protein 7
GSTM3 glutathione S-transferase mu 3 (brain)
HBP1 HMG-box transcription factor 1
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
ITM2A integral membrane protein 2A
KAT6B K(lysine) acetyltransferase 6B
KIAA0355 KIAA0355
KLHL24 kelch-like family member 24
LYRM1 LYR motif containing 1
NEFL neurofilament, light polypeptide
NR2F2 nuclear receptor subfamily 2, group F, member 2
NTS neurotensin
P3H2 prolyl 3-hydroxylase 2
PALLD palladin, cytoskeletal associated protein
PEG3 paternally expressed 3
PNRC1 proline-rich nuclear receptor coactivator 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RBM47 RNA binding motif protein 47
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SELENBP1 selenium binding protein 1
SFRP1 secreted frizzled-related protein 1
SFTPA2 surfactant protein A2
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
STAR steroidogenic acute regulatory protein
TACSTD2 tumor-associated calcium signal transducer 2
TPD52L1 tumor protein D52-like 1
TSC22D1 TSC22 domain family, member 1

decreased expression

Symbol Name
ADIRF adipogenesis regulatory factor
CA2 carbonic anhydrase II
CBR3 carbonyl reductase 3
CCND1 cyclin D1
CCNE2 cyclin E2
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
DENND2D DENN/MADD domain containing 2D
DUSP5 dual specificity phosphatase 5
GNAS GNAS complex locus
H1F0 H1 histone family, member 0
HOXA10 homeobox A10
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
JADE2 jade family PHD finger 2
JMJD6 jumonji domain containing 6
MARCKS myristoylated alanine-rich protein kinase C substrate
MMP1 matrix metallopeptidase 1
MTCL1 microtubule crosslinking factor 1
NCAM1 neural cell adhesion molecule 1
PCDH9 protocadherin 9
PLK2 polo-like kinase 2
PSCA prostate stem cell antigen
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
S100P S100 calcium binding protein P
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SPINK1 serine peptidase inhibitor, Kazal type 1
THBS1 thrombospondin 1
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TUBB2A tubulin, beta 2A class IIa
UBE2E3 ubiquitin-conjugating enzyme E2E 3
UPK1B uroplakin 1B