BRD-A18328003_GDC-0980_SKBR3_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

71 genes differentially expressed following the BRD-A18328003_GDC-0980_SKBR3_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADARB1 adenosine deaminase, RNA-specific, B1
ADRB2 adrenoceptor beta 2, surface
ANOS1 anosmin 1
ARHGAP32 Rho GTPase activating protein 32
ARID5B AT rich interactive domain 5B (MRF1-like)
CBX1 chromobox homolog 1
CES1 carboxylesterase 1
CLCA2 chloride channel accessory 2
CLU clusterin
CPB1 carboxypeptidase B1 (tissue)
CSRP2 cysteine and glycine-rich protein 2
CX3CR1 chemokine (C-X3-C motif) receptor 1
DOCK4 dedicator of cytokinesis 4
DSP desmoplakin
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
HNMT histamine N-methyltransferase
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
KAT6B K(lysine) acetyltransferase 6B
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCTD12 potassium channel tetramerization domain containing 12
LIMCH1 LIM and calponin homology domains 1
MEIS1 Meis homeobox 1
MTSS1 metastasis suppressor 1
MTUS1 microtubule associated tumor suppressor 1
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NRCAM neuronal cell adhesion molecule
PDZD2 PDZ domain containing 2
PELI1 pellino E3 ubiquitin protein ligase 1
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
SCGB2A2 secretoglobin, family 2A, member 2
SGK1 serum/glucocorticoid regulated kinase 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLIT2 slit homolog 2 (Drosophila)
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TMSB15A thymosin beta 15a
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
ZNF185 zinc finger protein 185 (LIM domain)

decreased expression

Symbol Name
ACTB actin, beta
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
CA2 carbonic anhydrase II
CCL2 chemokine (C-C motif) ligand 2
CD69 CD69 molecule
COL3A1 collagen, type III, alpha 1
COL6A2 collagen, type VI, alpha 2
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL8 chemokine (C-X-C motif) ligand 8
DCK deoxycytidine kinase
F3 coagulation factor III (thromboplastin, tissue factor)
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FHL2 four and a half LIM domains 2
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
HBD hemoglobin, delta
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IGHM immunoglobulin heavy constant mu
KIAA0125 KIAA0125
MMP3 matrix metallopeptidase 3
NID2 nidogen 2 (osteonidogen)
NNMT nicotinamide N-methyltransferase
OLFM4 olfactomedin 4
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
S100A2 S100 calcium binding protein A2
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
TCL1A T-cell leukemia/lymphoma 1A
TFPI2 tissue factor pathway inhibitor 2
TSPAN8 tetraspanin 8
TUBA4A tubulin, alpha 4a