BRD-A18328003_GDC-0980_PC3_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

159 genes differentially expressed following the BRD-A18328003_GDC-0980_PC3_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALCAM activated leukocyte cell adhesion molecule
ANG angiogenin, ribonuclease, RNase A family, 5
ANXA4 annexin A4
APOD apolipoprotein D
ATG14 autophagy related 14
BASP1 brain abundant, membrane attached signal protein 1
BEX1 brain expressed, X-linked 1
BEX4 brain expressed, X-linked 4
BHLHE41 basic helix-loop-helix family, member e41
C10ORF10 chromosome 10 open reading frame 10
CCNG2 cyclin G2
CD40 CD40 molecule, TNF receptor superfamily member 5
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CFB complement factor B
CHRDL1 chordin-like 1
CLIC5 chloride intracellular channel 5
CP ceruloplasmin (ferroxidase)
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
CTGF connective tissue growth factor
CXCL12 chemokine (C-X-C motif) ligand 12
DST dystonin
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
EAPP E2F-associated phosphoprotein
FABP4 fatty acid binding protein 4, adipocyte
FOXO4 forkhead box O4
GLS glutaminase
GPATCH8 G patch domain containing 8
GPNMB glycoprotein (transmembrane) nmb
GREB1 growth regulation by estrogen in breast cancer 1
GSN gelsolin
HBP1 HMG-box transcription factor 1
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST2H2BE histone cluster 2, H2be
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-E major histocompatibility complex, class I, E
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IDS iduronate 2-sulfatase
IGBP1 immunoglobulin (CD79A) binding protein 1
IGFBP7 insulin-like growth factor binding protein 7
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
INSR insulin receptor
IRS2 insulin receptor substrate 2
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5
KRT18 keratin 18, type I
KRT8 keratin 8, type II
LGALS8 lectin, galactoside-binding, soluble, 8
LXN latexin
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAOA monoamine oxidase A
MEF2C myocyte enhancer factor 2C
MUC16 mucin 16, cell surface associated
N4BP2L1 NEDD4 binding protein 2-like 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NET1 neuroepithelial cell transforming 1
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NT5E 5'-nucleotidase, ecto (CD73)
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
ORAI3 ORAI calcium release-activated calcium modulator 3
PAN2 PAN2 poly(A) specific ribonuclease subunit
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PRSS23 protease, serine, 23
PRUNE2 prune homolog 2 (Drosophila)
PTPRE protein tyrosine phosphatase, receptor type, E
PYCARD PYD and CARD domain containing
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RNASE4 ribonuclease, RNase A family, 4
RTN2 reticulon 2
S100P S100 calcium binding protein P
SEPP1 selenoprotein P, plasma, 1
SLC35E2B solute carrier family 35, member E2B
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SRGN serglycin
SSPN sarcospan
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STON1 stonin 1
SYT1 synaptotagmin I
TFF1 trefoil factor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TIMP3 TIMP metallopeptidase inhibitor 3
TM4SF1 transmembrane 4 L six family member 1
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TPP1 tripeptidyl peptidase I
TXNIP thioredoxin interacting protein
YPEL5 yippee-like 5 (Drosophila)
ZBTB16 zinc finger and BTB domain containing 16

decreased expression

Symbol Name
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
AK1 adenylate kinase 1
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
ATAD2 ATPase family, AAA domain containing 2
BHLHE40 basic helix-loop-helix family, member e40
BMP2 bone morphogenetic protein 2
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CA12 carbonic anhydrase XII
CCDC86 coiled-coil domain containing 86
CCNE2 cyclin E2
CDC25A cell division cycle 25A
CDC6 cell division cycle 6
DBF4 DBF4 zinc finger
DDIT4 DNA-damage-inducible transcript 4
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
EBP emopamil binding protein (sterol isomerase)
EIF5A eukaryotic translation initiation factor 5A
ENO1 enolase 1, (alpha)
FEN1 flap structure-specific endonuclease 1
FGFR3 fibroblast growth factor receptor 3
FKBP14 FK506 binding protein 14, 22 kDa
GAL galanin/GMAP prepropeptide
GINS2 GINS complex subunit 2 (Psf2 homolog)
GTF3A general transcription factor IIIA
HSPA14 heat shock 70kDa protein 14
IL13RA2 interleukin 13 receptor, alpha 2
JCHAIN joining chain of multimeric IgA and IgM
KRT10 keratin 10, type I
LMNB1 lamin B1
LTF lactotransferrin
MCM10 minichromosome maintenance complex component 10
MCM3 minichromosome maintenance complex component 3
MCM4 minichromosome maintenance complex component 4
MCM5 minichromosome maintenance complex component 5
MCM6 minichromosome maintenance complex component 6
MRTO4 mRNA turnover 4 homolog (S. cerevisiae)
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
NOP56 NOP56 ribonucleoprotein
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PBK PDZ binding kinase
PCNA proliferating cell nuclear antigen
PI3 peptidase inhibitor 3, skin-derived
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PPIF peptidylprolyl isomerase F
RAD51C RAD51 paralog C
RFC2 replication factor C (activator 1) 2, 40kDa
RHOB ras homolog family member B
RRAGD Ras-related GTP binding D
S100A2 S100 calcium binding protein A2
SACS sacsin molecular chaperone
SFN stratifin
SNRPB small nuclear ribonucleoprotein polypeptides B and B1
SRM spermidine synthase
TAGLN2 transgelin 2
TFRC transferrin receptor
TIPIN TIMELESS interacting protein
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMPO thymopoietin
TRIP13 thyroid hormone receptor interactor 13
TUBG1 tubulin, gamma 1
TYMS thymidylate synthetase
ZNF107 zinc finger protein 107